Top Iranian negotiator Saeed Jalili arrived in Iraqi capital Baghdad on Monday, in preparation for talks with world powers later this week over his country's nuclear programme.
He was welcomed by Iraqi Foreign Minister Hoshyar Zebari.
An Iranian delegation will meet representatives from the United States, Russia, China, Britain, France and Germany on Wednesday.
All six countries are at the forefront of trying to persuade Tehran to curb its nuclear programme and ease concerns it wants to use it to make nuclear weapons.
Jalili said his country hopes for a new beginning when the negotiations begin.
"We had an agreement in Istanbul," he said, referring to first round of talks in April. "That is the basis for the beginning of a new cooperation. We hope that the talks in Baghdad will be a kind of dialogue that will give shape to such cooperation," he said.
For its part, Iran will seek to stay looming US and European Union sanctions on its oil exports at the Baghdad talks.
The world powers will attempt to get Iran to commit to stop enriching uranium to a level that can be turned quickly into the fissile core of nuclear warheads, while ignoring, for now, its programme of lower enrichment, which would take longer to turn toward weapons-making.
Iran insists it is enriching uranium only to produce nuclear fuel and for cancer treatment.
Meanwhile, the head of the UN nuclear agency pushed on Monday for a breakthrough pact to resume inspections into suspected secret atomic weapons work and possibly set in motion further deal-making.
The mission by International Atomic Energy Agency chief Yukiya Amano - his first to Tehran since taking the post in 2009 - raised speculation about greater flexibility by Iranian officials as they struggle to balance the blows from Western sanctions and their insistence never to abandon the country's nuclear programme.