WORLD BREXIT REVIEW

SOURCE: AP HORIZONS, LIFESTYLE, HEALTH AND TECHNOLOGY / POOL

RESTRICTIONS: HORIZONS CLIENTS AND AP LIFESTYLE, HEALTH AND TECHNOLOGY CLIENTS ONLY

LENGTH: 6.44

SHOTLIST:

AP Television

London, UK - 22 February 2016

1. Wide of UK Houses of Parliament as London bus passes

2. Close of clock face at the top of Elizabeth Tower, which houses Big Ben

AP Television

London, UK - 16 June 2016

3. Wide of Big Ben as seen from Buckingham Palace

4. Wide of Buckingham Palace

POOL

London, UK - 3 June 2012

5. Queen Elizabeth II with Prince Philip (centre), Charles (left) and Camilla (right) on royal barge during Diamond Jubilee celebrations

6. Mid of Duke and Duchess of Cambridge and Prince Harry on royal barge

7. Pull out of royal barge sailing down River Thames during Diamond Jubilee celebrations

AP Television

London, UK - 11 June, 2016

8. Mid of Queen Elizabeth II in carriage during the Trooping of the Colour for her 90th birthday celebrations

9. Wide of Guardsmen in ceremonial marching during the celebrations

AP Television

London, UK - 1960s

++BLACK AND WHITE FOOTAGE / MUTE++

++4:3++

10. Close tilt down of man putting shirt in carrier bag

11. Wide of man by scooters

UNIVERSAL ARCHIVES

London, UK - 31 October 1963

++BLACK AND WHITE FOOTAGE / MUTE++

++4:3++

12. Various of Beatles getting off plane in London

AP Television

London, UK - 7 June 2016

++16:9++

13. SOUNDBITE (English) Robert Johnston, Fashion Director, GQ Magazine UK

"You also think street scene, you think east London, you think hipsters, you think the most vibrant street fashion possibly in the world."

AP Television

London, UK - 3 July 2012

14. Punk and goth street fashion in Camden

AP Television

London, UK - 16 June, 2016

15. Hipster in Brick Lane cafe

16. Pull focus of street sign reading: (English) "Brick Lane E1"

17. Various of curry houses on Brick Lane

AP Television

Margate, UK - 8 June 2016

18. Various of Margate beach and people relaxing in sunshine

19. SOUNDBITE (English) Iain Aitch, Author:

"Everyone might say a Sunday roast or fish and chips, that's a quintessentially British meal, but then suddenly everyone says it's chicken tikka masala."

20. Various of takeaway fish and chips being served

AP Television

London, United Kingdom, April 30, 1973 (MUTE)

++4:3++

21. Red buses on a London street

AP Television

London, United Kingdom, September 24, 1973 (MUTE)

++4:3++

22. Tilt down of Ford workers walking out of various plants

23. Wide of Ford cars on a train

24. Various men take part in industrial action at Ford plant

AP Television

United Kingdom, February 10, 1974 - no exact location available

++4:3++

25. Various of non functioning coal mines during national coal strike

AP Television

London, United Kingdom, June 3, 1975 (MUTE)

++4:3++

26. Mid of Margaret Thatcher wearing a flags-of-Europe sweater, flanked by women also wearing pro-Europe sweaters

AP Television

Maastricht, Netherlands - 7 June 2016

++16:9++

27. Clocktower of Maastricht town hall with EU, Limburg and Maastricht flags

28. Wide of streets in the town

AP Television

London, UK - 7 July 2016

29. Various of autistic teenager Rens Van Velzen completing other puzzles with black and yellow blocks against the clock

30. Close tilt down of the psychologist on the autism study at Kings College London timing Rens Van Velzen during test

31. Close of Van Velzen

32. SOUNDBITE (English) Professor Declan Murphy lead scientist, EU Aims study on autism, Kings College London:

"Big questions need big populations to come up with the right answers, and we simply cannot deliver the amount of patients for the amount of science from one centre or from one country."

33. Various of Van Velzen being tested in eye tracking unit at Kings College London

AP Television

Southampton, UK - 16 September 2016

34. Wide of Southampton Boat Show 2016, cruise ship in background

35. Tilt down to pontoon, boats and visitors

36. Close of 'Sunseeker' flag

37. Various of Sunseeker 95 Yacht exterior

38. SOUNDBITE (English) Phil Popham, CEO of Sunseeker International:

"We've benefited because of the weakness of the pound, but its all about business confidence."

39. Various of Fairline yacht

40. SOUNDBITE (English) Russell Currie, Managing Director of Fairline Yachts:

"We've had an overnight decrease in the price of our boats in areas such as the European market

41. Zoom out from cruise ship docked near boat show

42. SOUNDBITE (English) Howard Pridding, Chief Executive of British Marine:

"Industry and business need stability and the time it will take to exit from the European Union will be problematic"

AP Television

Mijas, Malaga - October 6, 2016

43. Wide of coastal area of Mijas

44. Pan of typical apartments in the area and people walking by the sea side

45. Various of British pensioners taking Spanish classes in the Parnell School

46. Various of Juan Mayor Carlos Maldonado in his office

47. SOUNDBITE (Spanish) Juan Carlos Maldonado, Mayor of Mijas:

"When the results of the Brexit (referendum) were known, a big uncertainty was created."

48. Various of family walking near beach

49. Pan from people walking up steps from the beach to the owner of Royal Beach cafe talking

50. SOUNDBITE (Spanish) Sergio Morales, co-owner of Royal Beach bar in Mijas:

"Most of our clients here, around 80% of them, are British."

AP Television

London, UK - 1 November 2016

51. Pull focus of bronze Japanese archer

52. Mid of men admiring antique chandelier

53. Art dealer Tanya Baxter showing painting to visitor

54. Close tilt down of painting 'Paper Bride in Waiting' by Zeng Chuanxing (price £120,000/ USD 147,000)

55. Wide of antique clock stand

AP Television

London, UK - 9 November 2016

56. Mid of Tiana Wilson with Santa who is holding a Hatchimal waiting for the toy to hatch

57. Wide of girl playing with toy on chair

58. Mid zoom in to boys playing with Bluetooth Furbys

59. Low mid view of caterpillar going past boys and Furbys

60. SOUNDBITE (English) Frederique Tutt, toy industry analyst, NPD:

"Since the Brexit vote the toy market has been faring really well with an increase of three percent."

AP Television

Lundby, Denmark - 22 November 2016

61. Mid tilt up of Christmas tree plantation

62. Wide of plantation through tops of trees

AP Television

Copenhagen, Denmark - 21 November 2016

63. SOUNDBITE (English) Claus Jerram Christensen, Managing Director of the Danish Christmas Tree Association:

"The low exchange rate for the sterling pound makes it more difficult to achieve the same prices."

64. Mid of large container truck filled with trees pulling out of yard stacked with trees

65. Pan across field of Christmas tree saplings for 2018 and beyond

LEADIN:

For decades Britain's discontent over its European Union (EU) membership has simmered on, but then came the June referendum.

Nationalism surfaced and Britain's voted to leave the EU.

Brexit as it became known sent shockwaves through money markets and governments around the world.

STORYLINE:

In the weeks running up to referendum judgement day, the British were busy with a little soul searching.

Mulling over their shared history, the country's pride in their democracy and heritage.

It was a year when Queen Elizabeth celebrated being the longest reigning UK monarch and the country celebrated her ninetieth birthday.

The pomp and ceremony from her recent jubilee were still a source of pride and were reminiscent of the heydays when London style was considered to be world leading.

In the 1960's British fashion and British pop were riding high.

That sense of being at the vanguard of style has continued, according to Robert Johnston the Fashion Director of GQ Magazine: "You also think street scene, you think east London, you think hipsters, you think the most vibrant street fashion possibly in the world."

Author Iain Aitch explained how a variety of heritages were now mixed up, making Britishness a more complex idea to communicate: "Everyone might say a Sunday roast or fish and chips, that's a quintessentially British meal, but then suddenly everyone says it's chicken tikka masala."

But it wasn't this hipster, Brick Lane art and curry house side of Britain that won the vote.

The referendum on June 23rd was to signal the start of a long debate.

Britons for the first time had to absorb what being outside of the EU looked like.

Britain joined what was then called the European Economic Community in January 1973.

This was ratified by a referendum in 1975 with a resounding 67% majority.

By the seventies, Britain was beset by strikes and disgruntled union workers.

Traditional industries such as manufacturing and coal were in decline in the mid seventies.

Unemployment exceeded one million for the first time in March 1975. By the August that figure had increased to 1.25 million.

Some 83,000 immigrants were living in the UK by 1975, mostly from the Commonwealth.

According to Migration Watch UK for the year ending December 2015, net migration to the UK was 333,000.

And the lady had yet to turn. Margaret Thatcher MP (then leader of the opposition) campaigned to stay in the European Economic Community.

Later as prime minister between 1979 and 1990, Thatcher was known for her tough line with Brussels, especially during negotiations for the Maastrict Treaty in 1992.

The city of Maastrict is the home of the treaty which created the EU.

As summer arrived, businesses, leading universities and research establishments were beginning to assess the impact of Brexit.

For science and medicine, concerns were two fold.

Britain had attracted thousands of top researchers as well as billions of Euros in grants.

They went into research like this at Kings College London.

This project is a multidisciplinary look at the potential causes and effects of autism. It's a long term project which is linked to other studies across Europe.

Doctors and scientists aren't worried about losing cash in the short term, but falling behind in the knowledge race in the long term, especially as Britain has sought to place itself as a central base for the new industrial technologies.

The other fear is losing the brains which have been drawn to British research, people who now fear they will need to move to other institutions to keep up with the cash and the research.

Lead scientist at King's College Professor Declan Murphy warned: "Big questions need big populations to come up with the right answers, and we simply cannot deliver the amount of patients for the amount of science from one centre from one country."

The EU's Horizon 2020 budget is 80-billion Euro which funds medicine and science research across Europe.

Britain's split from the EU will leave a funding gap as well as a brain drain, according to Murphy. He argues it will be the children with autism like Van Velzen who will lose out.

As an island nation, boat building and sales have been important to the UK.

The industry fears rough waters may be ahead for Britain's luxury yacht industry, but right now it's riding on a wave caused by the plunge in the pound's value.

Phil Popham, the CEO of Sunseeker International was cautious: "We've benefited because of the weakness of the pound, but its all about business confidence."

Others like Russell Currie, the Managing Director of Fairline Yachts, says he already had cause to worry: "We've had an overnight decrease in the price of our boats in areas such as the European market."

British Marine's chief executive Howard Pridding tried to show more confidence in the course ahead: "Obviously, industry and business need stability and the time it will take to exit from the European Union will be problematic."

An estimated 1.2 million Britons live in other EU countries, mostly France, Portugal and Spain according to Britain's House of Commons library.

But that's a conservative figure because many expats don't bother registering with their embassies or the local authorities.

At Mijas on Spain's Costa del Sol, many Brits don't want to return to Blighty.

Used to the sun, sea and cafe society, some British residents are so concerned that their lives on the Costas are threatened, that after many years they're finally learning to speak Spanish.

According to Mijas' Mayor Juan Carlos Maldonado: "When the results of the Brexit (referendum) were known, a big uncertainty was created."

Local traders are also keen to keep the British on the Costa.

Many are retired and spend their pensions here.

Bar owner Sergio Morales says: "Most of our clients here, around 80% of them, are British."

A cloud of uncertainty still hangs over British expats in Spain and elsewhere in Europe.

And it's possible a string of similar nationality schools for expats may spring up.

Not everyone was bemoaning the onset of Brexit.

The art and antique market experienced a mini boom according to London dealers at this winter fair.

The weak pound against the dollar and Euro has seen American collectors in particular start to snap up bargains with savings of beween 25 and 30 per cent compared with six months ago.

Art dealers are reporting a similar trend.

They say investors see the arts market as a safe refuge in uncertain times.

As Christmas approaches the toy industry is bracing itself and Santa is wondering whether he'll have much to be jolly about.

It's the time of year when manufacturers and retailers count on making their biggest cash bonus of the year.

According to industry analyst Frederique Tutt: "Since the Brexit vote the toy market has been faring really well with an increase of three percent."

That's because toy retailers buy stock almost a year in advance and can keep prices stable, but the toy dealers here admit next year the stockings left out for Father Chrismas may have shrunk considerably.

There's nothing as Christmassy as a Christmas tree, but in Denmark the outlook for tree producers isn't quite so evergreen.

According to the Danish Christmas Tree Association, the small Scandinavian country grows around 11.5 million trees a year.

About 9.5 million of those are exported.

But these are challenging times and currency fluctuations are having an effect on trade.

Speaking about his members, Claus Jerram Christensen of the Danish Christmas Tree Association says: "They have experienced that the low exchange rate for the sterling pound makes it more difficult to achieve the same prices."

The true impact of Brexit on Britain and Europe as a whole is still to an extent unknown.

The UK government had announced it was to trigger Article 50 next March to start negotiations to leave EU.

But since then, Brexit has twice been contested in the High Court.

One ruling has already stated Britain's law makers should be allowed a vote in Parliament beforehand.

Breaking up, it seems, really is hard to do.

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LEAD IN:

Virtual and augmented reality, health technology and mobile tech are taking centre stage at the annual TechCrunch Disrupt startup event in London.

According to a recent report, the British capital remains Europe's biggest tech hub despite the recent 'Leave' EU vote.

Experts say how migration is managed once Britain leaves the 28-nation bloc could be pivotal for the city's future tech scene.

STORY-LINE:

During London's 2012 Olympic Games, the Copper Box Arena hosted fencing duels and handball matches.

Four years on, a completely different type of competition is hotting up.

At TechCrunch Disrupt London, an annual tech conference, fledgling companies are competing for venture capitalists' attention in 'Start-Up Alley' and 'Battlefield' areas.

The 'Startup Battlefield' gives entrants the chance to feverishly pitch their company to a panel of judges. The winning team takes away a prize of 50,000 US dollars.

Virtual reality is a hot tech trend currently, but high-cost headsets mean many are yet to sample premium VR content.

Poland-based RiftCat is aiming to change that.

Its developers created PC technology that allows gamers to play high-quality VR games through simple mobile VR viewers like Google Cardboard.

VRidge - as it's called - is intended to act as a bridge between mobile and PC VR content.

"When you have two branches of virtual reality, the PC VR and mobile VR and they both have their advantages and disadvantages - PC VR is the highest quality, but it's expensive and mobile VR is cheap because you can use your phone and put it, you have only the lenses, but it has not that much capability," explains Marek Antoniuk from RiftCat.

"So, basically we are making a bridge in between these two worlds."

Hot on the heels of virtual reality, augmented reality - or AR - is becoming a popular topic following the global success of smartphone game 'Pokemon Go'.

Liverpool-based SwapBots created an augmented reality game which seemingly brings simple cardboard toys to life.

Users can combine boxes to create different characters, there's a variety of single and multiplayer games for players to explore.

"When you're young yourself, you imagine your toys coming to life," explains Phil Charnock from SwapBots.

"And now you can - I won't say replace your imagination - but you can kind of see your imagination living on the screen.

"You can see the toy itself, starting to move around, see them battle with each other and I think that's an incredible thing to be feeding kids' imaginations like that."

Medtech company xRapid is demonstrating its automated diagnostic smartphone app, designed to diagnose diseases such as malaria and tuberculosis.

Using the smartphone's camera and when connected to a microscope, the app deploys digital imaging and artificial intelligence to analyse smear tests.

It's claimed the technology is particularly useful in remote areas, far from trained doctors or a reliable internet connection.

"We take a blood sample, we use any kind of microscope and with the iPhone app that we developed, we can tell you if you are sick or not, give all the important details to the doctor to give the right diagnostic and the right treatment to patients," explains Charles Van Overmeire from xRapid.

Seoul-based Attocube is demonstrating its smartphone-connected wooden blocks, designed to inspire and educate young minds.

Players are challenged to create various letters, numbers and shapes using cubes decorated with different geometric patterns.

The idea is to boost creativity and problem solving while still giving children screen time.

"We created this cube and children learn the alphabet or numbers or images and create different patterns, and they make more and more creative, and (the) brain strengthens, yeah," explains Johnny Moon from Attocube.

London-based Firef.ly is demonstrating its mobile travel app which combines planning, guides and journals all in one place.

Users can browse guidebooks, add locations to Buck Lists, shoot and embed videos and photos onto a map, and tailor digital postcards for friends and family back home.

The idea is to provide all smartphone-enabled travellers require in one app.

"You look at Facebook, it's great for peeling through somebody's wall, but it's a sporadic hit of a bunch of different things, it doesn't join up the story," explains Chad Cribbins from Firef.ly.

"So, ours is uniquely dedicated to a journal of your travels, that you can peel back through time.

"So, all these lines that we capture, over months and months, even just living in London, becomes an interesting narrative for you to hold onto."

Despite Britain's recent 'Leave' EU vote, London appears to be maintaining its place as Europe's tech capital.

According to the recent 'State of European Tech' report by tech investment firm Atomico, London boasts over 300,000 developers.

French capital Paris came in second with over 134,000 - less than half London's total.

"It still remains, whatever you want to say about Brexit or anything else, London and the UK is still the biggest hub of startup ecosystems in the whole of Europe and that's really not going to change anytime soon," says Mike Butcher from tech website TechCrunch.

Despite that, Butcher says how Britain handles migration once it exits the 28-nation bloc could be pivotal for London's startup scene.

"It's going to be about talent because migration and skilled migration are hugely at the core of startups," he says.

"You know, the two things that affect startups are money and talent, and talent is really going to be affected by Brexit, how people get visas, how people access the UK, and how people are able to hire into the UK.

"Brexit is absolutely the core of this conversation about startups today."

TechCrunch Disrupt London 2016 runs 5-6 December at the Copper Box Arena in London's Queen Elizabeth Olympic Park.

London, UK - 5 December 2016

1. High wide shot of TechCrunch Disrupt London 2016 show floor

2. Wide of booths and attendees

3. Tilt down from 'Startup Battlefield' sign to show floor

4. Various of Marek Antoniuk, RiftCat, demonstrating RiftCat VRidge virtual reality technology

5. SOUNDBITE (English) Marek Antoniuk, RiftCat:

"When you have two branches of virtual reality, the PC VR and mobile VR and they both have their advantages and disadvantages - PC VR is the highest quality, but it's expensive and mobile VR is cheap because you can use your phone and put it, you have only the lenses, but it has not that much capability. So, basically we are making a bridge in between these two worlds."

6. Low shot of attendee removing virtual reality headset

7. Various of Phil Charnock, SwapBots, demonstrating SwapBots augmented reality toys

8. SOUNDBITE (English) Phil Charnock, SwapBots:

"When you're young yourself, you imagine your toys coming to life. And now you can - I won't say replace your imagination - but you can kind of see your imagination actually living on the screen. You can see the toy itself, starting to move around, see them battle with each other and I think that's an incredible thing to be feeding kids' imaginations like that."

9. Pull out from SwapBots toy to tablet showing augmented reality technology

10. Various of Charles Van Overmeire, xRapid, demonstrating xRapid automated diagnostic app with microscope

11. SOUNDBITE (English) Charles Van Overmeire, xRapid:

"We take a blood sample, we use any kind of microscope and with the iPhone app that we developed, we can tell you if you are sick or not, we give all the important details to the doctor to give the right diagnostic and the right treatment to patients."

12. Various of Johnny Moon, Attocube, demonstrating Attocube smartphone-connected wooden block learning game

13. Tilt up of smartphone showing Attocube app and complete letter 'D'

14. Pull out of blocks showing completed letter 'D'

15. SOUNDBITE (English) Johnny Moon, Attocube:

"We created this cube and children learn the alphabet or numbers or images and create different patterns, and they make more and more creative, and (the) brain strengthens, yeah."

16. Various of Chad Cribbins, Firef.ly, demonstrating Firef.ly travel smartphone app

17. SOUNDBITE (English) Chad Cribbins, Firef.ly:

"You look at Facebook, it's great for peeling through somebody's wall, but it's a sporadic hit of a bunch of different things, it doesn't join up the story. So, ours is uniquely dedicated to a journal of your travels, that you can peel back through time. So, all these lines that we capture, over months and months, even just living in London, becomes an interesting narrative for you to hold onto."

18. Wide tilt down to TechCrunch Disrupt London 2016 show floor

19. Wide of sign, reading (English): 'Startup Battlefield'

20. Various of booths and attendees

21. SOUNDBITE (English) Mike Butcher, Editor At Large, TechCrunch:

"It still remains, whatever you want to say about Brexit or anything else, London and the UK is still the biggest hub of startup ecosystems in the whole of Europe and that's really not going to change anytime soon."

22. Various of booths and attendees

23. SOUNDBITE (English) Mike Butcher, Editor At Large, TechCrunch:

"It's going to be about talent because migration and skilled migration are hugely at the core of startups. You know, the two things that affect startups are money and talent, and talent is really going to be affected by Brexit, how people get visas, how people access the UK, and how people are able to hire into the UK. Brexit is absolutely the core of this conversation about startups today."

24. Tilt down to TechCrunch Disrupt London 2016 show floor

25. Close of tank robot toy moving

LEAD IN:

Virtual and augmented reality, health technology and mobile tech are taking centre stage at the annual TechCrunch Disrupt startup event in London.

According to a recent report, the British capital remains Europe's biggest tech hub despite the recent 'Leave' EU vote.

Experts say how migration is managed once Britain leaves the 28-nation bloc could be pivotal for the city's future tech scene.

STORY-LINE:

During London's 2012 Olympic Games, the Copper Box Arena hosted fencing duels and handball matches.

Four years on, a completely different type of competition is hotting up.

At TechCrunch Disrupt London, an annual tech conference, fledgling companies are competing for venture capitalists' attention in 'Start-Up Alley' and 'Battlefield' areas.

The 'Startup Battlefield' gives entrants the chance to feverishly pitch their company to a panel of judges. The winning team takes away a prize of 50,000 US dollars.

Virtual reality is a hot tech trend currently, but high-cost headsets mean many are yet to sample premium VR content.

Poland-based RiftCat is aiming to change that.

Its developers created PC technology that allows gamers to play high-quality VR games through simple mobile VR viewers like Google Cardboard.

VRidge - as it's called - is intended to act as a bridge between mobile and PC VR content.

"When you have two branches of virtual reality, the PC VR and mobile VR and they both have their advantages and disadvantages - PC VR is the highest quality, but it's expensive and mobile VR is cheap because you can use your phone and put it, you have only the lenses, but it has not that much capability," explains Marek Antoniuk from RiftCat.

"So, basically we are making a bridge in between these two worlds."

Hot on the heels of virtual reality, augmented reality - or AR - is becoming a popular topic following the global success of smartphone game 'Pokemon Go'.

Liverpool-based SwapBots created an augmented reality game which seemingly brings simple cardboard toys to life.

Users can combine boxes to create different characters, there's a variety of single and multiplayer games for players to explore.

"When you're young yourself, you imagine your toys coming to life," explains Phil Charnock from SwapBots.

"And now you can - I won't say replace your imagination - but you can kind of see your imagination living on the screen.

"You can see the toy itself, starting to move around, see them battle with each other and I think that's an incredible thing to be feeding kids' imaginations like that."

Medtech company xRapid is demonstrating its automated diagnostic smartphone app, designed to diagnose diseases such as malaria and tuberculosis.

Using the smartphone's camera and when connected to a microscope, the app deploys digital imaging and artificial intelligence to analyse smear tests.

It's claimed the technology is particularly useful in remote areas, far from trained doctors or a reliable internet connection.

"We take a blood sample, we use any kind of microscope and with the iPhone app that we developed, we can tell you if you are sick or not, give all the important details to the doctor to give the right diagnostic and the right treatment to patients," explains Charles Van Overmeire from xRapid.

Seoul-based Attocube is demonstrating its smartphone-connected wooden blocks, designed to inspire and educate young minds.

Players are challenged to create various letters, numbers and shapes using cubes decorated with different geometric patterns.

The idea is to boost creativity and problem solving while still giving children screen time.

"We created this cube and children learn the alphabet or numbers or images and create different patterns, and they make more and more creative, and (the) brain strengthens, yeah," explains Johnny Moon from Attocube.

London-based Firef.ly is demonstrating its mobile travel app which combines planning, guides and journals all in one place.

Users can browse guidebooks, add locations to Buck Lists, shoot and embed videos and photos onto a map, and tailor digital postcards for friends and family back home.

The idea is to provide all smartphone-enabled travellers require in one app.

"You look at Facebook, it's great for peeling through somebody's wall, but it's a sporadic hit of a bunch of different things, it doesn't join up the story," explains Chad Cribbins from Firef.ly.

"So, ours is uniquely dedicated to a journal of your travels, that you can peel back through time.

"So, all these lines that we capture, over months and months, even just living in London, becomes an interesting narrative for you to hold onto."

Despite Britain's recent 'Leave' EU vote, London appears to be maintaining its place as Europe's tech capital.

According to the recent 'State of European Tech' report by tech investment firm Atomico, London boasts over 300,000 developers.

French capital Paris came in second with over 134,000 - less than half London's total.

"It still remains, whatever you want to say about Brexit or anything else, London and the UK is still the biggest hub of startup ecosystems in the whole of Europe and that's really not going to change anytime soon," says Mike Butcher from tech website TechCrunch.

Despite that, Butcher says how Britain handles migration once it exits the 28-nation bloc could be pivotal for London's startup scene.

"It's going to be about talent because migration and skilled migration are hugely at the core of startups," he says.

"You know, the two things that affect startups are money and talent, and talent is really going to be affected by Brexit, how people get visas, how people access the UK, and how people are able to hire into the UK.

"Brexit is absolutely the core of this conversation about startups today."

TechCrunch Disrupt London 2016 runs 5-6 December at the Copper Box Arena in London's Queen Elizabeth Olympic Park.

London, UK - 5 December 2016

1. High wide shot of TechCrunch Disrupt London 2016 show floor

2. Wide of booths and attendees

3. Tilt down from 'Startup Battlefield' sign to show floor

4. Various of Marek Antoniuk, RiftCat, demonstrating RiftCat VRidge virtual reality technology

5. SOUNDBITE (English) Marek Antoniuk, RiftCat:

"When you have two branches of virtual reality, the PC VR and mobile VR and they both have their advantages and disadvantages - PC VR is the highest quality, but it's expensive and mobile VR is cheap because you can use your phone and put it, you have only the lenses, but it has not that much capability. So, basically we are making a bridge in between these two worlds."

6. Low shot of attendee removing virtual reality headset

7. Various of Phil Charnock, SwapBots, demonstrating SwapBots augmented reality toys

8. SOUNDBITE (English) Phil Charnock, SwapBots:

"When you're young yourself, you imagine your toys coming to life. And now you can - I won't say replace your imagination - but you can kind of see your imagination actually living on the screen. You can see the toy itself, starting to move around, see them battle with each other and I think that's an incredible thing to be feeding kids' imaginations like that."

9. Pull out from SwapBots toy to tablet showing augmented reality technology

10. Various of Charles Van Overmeire, xRapid, demonstrating xRapid automated diagnostic app with microscope

11. SOUNDBITE (English) Charles Van Overmeire, xRapid:

"We take a blood sample, we use any kind of microscope and with the iPhone app that we developed, we can tell you if you are sick or not, we give all the important details to the doctor to give the right diagnostic and the right treatment to patients."

12. Various of Johnny Moon, Attocube, demonstrating Attocube smartphone-connected wooden block learning game

13. Tilt up of smartphone showing Attocube app and complete letter 'D'

14. Pull out of blocks showing completed letter 'D'

15. SOUNDBITE (English) Johnny Moon, Attocube:

"We created this cube and children learn the alphabet or numbers or images and create different patterns, and they make more and more creative, and (the) brain strengthens, yeah."

16. Various of Chad Cribbins, Firef.ly, demonstrating Firef.ly travel smartphone app

17. SOUNDBITE (English) Chad Cribbins, Firef.ly:

"You look at Facebook, it's great for peeling through somebody's wall, but it's a sporadic hit of a bunch of different things, it doesn't join up the story. So, ours is uniquely dedicated to a journal of your travels, that you can peel back through time. So, all these lines that we capture, over months and months, even just living in London, becomes an interesting narrative for you to hold onto."

18. Wide tilt down to TechCrunch Disrupt London 2016 show floor

19. Wide of sign, reading (English): 'Startup Battlefield'

20. Various of booths and attendees

21. SOUNDBITE (English) Mike Butcher, Editor At Large, TechCrunch:

"It still remains, whatever you want to say about Brexit or anything else, London and the UK is still the biggest hub of startup ecosystems in the whole of Europe and that's really not going to change anytime soon."

22. Various of booths and attendees

23. SOUNDBITE (English) Mike Butcher, Editor At Large, TechCrunch:

"It's going to be about talent because migration and skilled migration are hugely at the core of startups. You know, the two things that affect startups are money and talent, and talent is really going to be affected by Brexit, how people get visas, how people access the UK, and how people are able to hire into the UK. Brexit is absolutely the core of this conversation about startups today."

24. Tilt down to TechCrunch Disrupt London 2016 show floor

25. Close of tank robot toy moving

LEAD IN:

Virtual and augmented reality, health technology and mobile tech are taking centre stage at the annual TechCrunch Disrupt startup event in London.

According to a recent report, the British capital remains Europe's biggest tech hub despite the recent 'Leave' EU vote.

Experts say how migration is managed once Britain leaves the 28-nation bloc could be pivotal for the city's future tech scene.

STORY-LINE:

During London's 2012 Olympic Games, the Copper Box Arena hosted fencing duels and handball matches.

Four years on, a completely different type of competition is hotting up.

At TechCrunch Disrupt London, an annual tech conference, fledgling companies are competing for venture capitalists' attention in 'Start-Up Alley' and 'Battlefield' areas.

The 'Startup Battlefield' gives entrants the chance to feverishly pitch their company to a panel of judges. The winning team takes away a prize of 50,000 US dollars.

Virtual reality is a hot tech trend currently, but high-cost headsets mean many are yet to sample premium VR content.

Poland-based RiftCat is aiming to change that.

Its developers created PC technology that allows gamers to play high-quality VR games through simple mobile VR viewers like Google Cardboard.

VRidge - as it's called - is intended to act as a bridge between mobile and PC VR content.

"When you have two branches of virtual reality, the PC VR and mobile VR and they both have their advantages and disadvantages - PC VR is the highest quality, but it's expensive and mobile VR is cheap because you can use your phone and put it, you have only the lenses, but it has not that much capability," explains Marek Antoniuk from RiftCat.

"So, basically we are making a bridge in between these two worlds."

Hot on the heels of virtual reality, augmented reality - or AR - is becoming a popular topic following the global success of smartphone game 'Pokemon Go'.

Liverpool-based SwapBots created an augmented reality game which seemingly brings simple cardboard toys to life.

Users can combine boxes to create different characters, there's a variety of single and multiplayer games for players to explore.

"When you're young yourself, you imagine your toys coming to life," explains Phil Charnock from SwapBots.

"And now you can - I won't say replace your imagination - but you can kind of see your imagination living on the screen.

"You can see the toy itself, starting to move around, see them battle with each other and I think that's an incredible thing to be feeding kids' imaginations like that."

Medtech company xRapid is demonstrating its automated diagnostic smartphone app, designed to diagnose diseases such as malaria and tuberculosis.

Using the smartphone's camera and when connected to a microscope, the app deploys digital imaging and artificial intelligence to analyse smear tests.

It's claimed the technology is particularly useful in remote areas, far from trained doctors or a reliable internet connection.

"We take a blood sample, we use any kind of microscope and with the iPhone app that we developed, we can tell you if you are sick or not, give all the important details to the doctor to give the right diagnostic and the right treatment to patients," explains Charles Van Overmeire from xRapid.

Seoul-based Attocube is demonstrating its smartphone-connected wooden blocks, designed to inspire and educate young minds.

Players are challenged to create various letters, numbers and shapes using cubes decorated with different geometric patterns.

The idea is to boost creativity and problem solving while still giving children screen time.

"We created this cube and children learn the alphabet or numbers or images and create different patterns, and they make more and more creative, and (the) brain strengthens, yeah," explains Johnny Moon from Attocube.

London-based Firef.ly is demonstrating its mobile travel app which combines planning, guides and journals all in one place.

Users can browse guidebooks, add locations to Buck Lists, shoot and embed videos and photos onto a map, and tailor digital postcards for friends and family back home.

The idea is to provide all smartphone-enabled travellers require in one app.

"You look at Facebook, it's great for peeling through somebody's wall, but it's a sporadic hit of a bunch of different things, it doesn't join up the story," explains Chad Cribbins from Firef.ly.

"So, ours is uniquely dedicated to a journal of your travels, that you can peel back through time.

"So, all these lines that we capture, over months and months, even just living in London, becomes an interesting narrative for you to hold onto."

Despite Britain's recent 'Leave' EU vote, London appears to be maintaining its place as Europe's tech capital.

According to the recent 'State of European Tech' report by tech investment firm Atomico, London boasts over 300,000 developers.

French capital Paris came in second with over 134,000 - less than half London's total.

"It still remains, whatever you want to say about Brexit or anything else, London and the UK is still the biggest hub of startup ecosystems in the whole of Europe and that's really not going to change anytime soon," says Mike Butcher from tech website TechCrunch.

Despite that, Butcher says how Britain handles migration once it exits the 28-nation bloc could be pivotal for London's startup scene.

"It's going to be about talent because migration and skilled migration are hugely at the core of startups," he says.

"You know, the two things that affect startups are money and talent, and talent is really going to be affected by Brexit, how people get visas, how people access the UK, and how people are able to hire into the UK.

"Brexit is absolutely the core of this conversation about startups today."

TechCrunch Disrupt London 2016 runs 5-6 December at the Copper Box Arena in London's Queen Elizabeth Olympic Park.

London, UK - 5 December 2016

1. High wide shot of TechCrunch Disrupt London 2016 show floor

2. Wide of booths and attendees

3. Tilt down from 'Startup Battlefield' sign to show floor

4. Various of Marek Antoniuk, RiftCat, demonstrating RiftCat VRidge virtual reality technology

5. SOUNDBITE (English) Marek Antoniuk, RiftCat:

"When you have two branches of virtual reality, the PC VR and mobile VR and they both have their advantages and disadvantages - PC VR is the highest quality, but it's expensive and mobile VR is cheap because you can use your phone and put it, you have only the lenses, but it has not that much capability. So, basically we are making a bridge in between these two worlds."

6. Low shot of attendee removing virtual reality headset

7. Various of Phil Charnock, SwapBots, demonstrating SwapBots augmented reality toys

8. SOUNDBITE (English) Phil Charnock, SwapBots:

"When you're young yourself, you imagine your toys coming to life. And now you can - I won't say replace your imagination - but you can kind of see your imagination actually living on the screen. You can see the toy itself, starting to move around, see them battle with each other and I think that's an incredible thing to be feeding kids' imaginations like that."

9. Pull out from SwapBots toy to tablet showing augmented reality technology

10. Various of Charles Van Overmeire, xRapid, demonstrating xRapid automated diagnostic app with microscope

11. SOUNDBITE (English) Charles Van Overmeire, xRapid:

"We take a blood sample, we use any kind of microscope and with the iPhone app that we developed, we can tell you if you are sick or not, we give all the important details to the doctor to give the right diagnostic and the right treatment to patients."

12. Various of Johnny Moon, Attocube, demonstrating Attocube smartphone-connected wooden block learning game

13. Tilt up of smartphone showing Attocube app and complete letter 'D'

14. Pull out of blocks showing completed letter 'D'

15. SOUNDBITE (English) Johnny Moon, Attocube:

"We created this cube and children learn the alphabet or numbers or images and create different patterns, and they make more and more creative, and (the) brain strengthens, yeah."

16. Various of Chad Cribbins, Firef.ly, demonstrating Firef.ly travel smartphone app

17. SOUNDBITE (English) Chad Cribbins, Firef.ly:

"You look at Facebook, it's great for peeling through somebody's wall, but it's a sporadic hit of a bunch of different things, it doesn't join up the story. So, ours is uniquely dedicated to a journal of your travels, that you can peel back through time. So, all these lines that we capture, over months and months, even just living in London, becomes an interesting narrative for you to hold onto."

18. Wide tilt down to TechCrunch Disrupt London 2016 show floor

19. Wide of sign, reading (English): 'Startup Battlefield'

20. Various of booths and attendees

21. SOUNDBITE (English) Mike Butcher, Editor At Large, TechCrunch:

"It still remains, whatever you want to say about Brexit or anything else, London and the UK is still the biggest hub of startup ecosystems in the whole of Europe and that's really not going to change anytime soon."

22. Various of booths and attendees

23. SOUNDBITE (English) Mike Butcher, Editor At Large, TechCrunch:

"It's going to be about talent because migration and skilled migration are hugely at the core of startups. You know, the two things that affect startups are money and talent, and talent is really going to be affected by Brexit, how people get visas, how people access the UK, and how people are able to hire into the UK. Brexit is absolutely the core of this conversation about startups today."

24. Tilt down to TechCrunch Disrupt London 2016 show floor

25. Close of tank robot toy moving

FOR CLEAN VERSION SEE STORY NUMBER: 4045006

LEAD IN:

Scientists controlling EU projects worth millions of dollars say the British exit from Europe risks the future of medical research, and may endanger future treatments for cancer and children.

Research projects at Kings and University Colleges in London rely on the collaboration of hundreds of doctors and multidisciplinary scientists across Europe - which could come under threat because of Brexit.

STORY-LINE:

Precision medicine is changing the future for cancer patients.

This lab at University College London has devised a safer and simpler alternative to standard radioactive techniques of imaging tumours.

Professor Xavier Golay's team has discovered a way to make a tumour light up with a simple sugar solution.

Because the solution is not radioactive is doesn't carry the same side effects which make patients sick.

It means radiodlogists can see tumours in more detail and check them more frequently.

That in turn allows doctors to personalise drug treatments for the patient.

They can respond more quickly, seeing what works and what doesn't and that speed could save more lives.

The team here is about to begin a trial on the new imaging technique thanks to a six and a half million Euro grant from the European Union.

The whole university has 103-million Euros to fund medical and science projects over the next few years.

All currently funded projects will be allowed to complete - but it's what happens next that's vexing doctors and scientist who argue breakthroughs don't come to order at the end of one trial.

Golay says for the vast majority of scientists in Britain the result of the recent EU referendum - for the UK to exit - was a shock.

Golay says it's not just the money which will risk future projects like this.

His team - like most university and hospital research groups - comes from all over the European Union.

Collaboration on this imaging project is with other specialist scientists at the Max Planck Institute in Germany as well as other units including France and Italy.

He's already concerned about the future.

"I've heard of at least two, three very senior people who've said okay right, now I'm taking all my grant with me and I'm going back to Germany, Switzerland, France because actually, in that way, they know they'll still have access and it's not only access to funding because the funding is great in this country, it is really good. It's really (about) access to funding and this opportunity to collaborate."

At preschool age Rens Van Velzen's parents realised he was struggling with dyslexia, but when he went to school it became clear he was autistic.

Van Velzen, now a highly intelligent fifteen year old, is part of Europe's largest study into mental health disorder.

Here researchers like Hannah Haywood combine genetics, neuroimaging, cognitive testing and clinical assessments to try to discover what are the causes.

The research project called EU Aims is carried out here at Kings College London in collaboration with scientists in other centres of Europe.

Costing 32 million Euros it's also the biggest grant given to any one project.

Autism Spectrum Disorder is a developmental problem which affects the way people interact with the world around them.

People are affected differently and scientists want to understand why those differences occur.

Haywood says: "One can go on to a life where they never speak, they are highly affected and quite disabled. Another person can go on (to be) fully verbal and become a professor at Cambridge (University) and someone else can go on and live a full life with marriage and children, why does that happen? Why does it affect people so differently when it's effectively the same condition. So we're trying to answer those questions, we're trying to understand why it affects different people in different ways and I think the thing that really attracted me to the project is because, we're trying to highlight the great skills and strengths in this group as well as the things that people find difficult."

The goal is to identify biomarkers and develop drug treatments.

It's a long term study, but how long can it continue here and what happens to the research after the current funding ends in 2020?

Rens Van Velzen is already preparing for A-levels in maths, chemistry and physics.

But his autism means life outside the classroom is not always straightforward.

He explains: "Quite often when talking peer to peer, the other person can get frustrated with how I respond because they're (I'm) not responding the way that they're expecting me to respond as the people usually do. So quite often I don't pick up someone's annoyed, or that sort of thing. It's very hard to explain because I haven't had the experience of not having autism."

Haywood, like others on the team, is convinced the project must be protected and fears Britain leaving the EU will end large scale endeavours like this which progress more steadily because of the wide collaboration among doctors and scientists.

She says: "Quite often there can be a lot of negativity around being diagnosed and living with the condition and in my work, I've worked with autism for twelve years, I have met some of the most skilled and highly intelligent people."

Van Velzen has been part of the study since it started.

Now he's hoping for a career in astrophysics.

"I think I'll work on either discovering more about our universe and our place in it, or working on ways to get to other parts of the universe," says Van Velzen.

After completing puzzles in record time he goes on for tests in the eye tracking unit.

Studies have used eye-tracing technology to see how long autistic children spend looking at the social and non-social features in a series of images on pictures and videos like these.

Ren's mother Jose Van Velzen is a cognitive neuroscientist herself although she does not work on this project.

While she is confident about her son's academic success she worries about how he will cope with work and whether he will find happiness in personal relationships.

She says: "It is sometimes challenging for Rens to keep track of what the person he's talking to is feeling and how he's being perceived. He's very much driven by telling things as they are, or how he sees them and of course in normal interaction, in normal relationships you constantly monitor what the other person is thinking. That's definitely very challenging for him and he is aware that this is one of his weaknesses he needs to work on he cannot always deal with it at that particular time and I think that is something in general that will make relationships and work environments quite a challenging place for him."

According to scientists here this project is the first of it kind in the world developing the infrastructure which will underpin new treatments for autism.

There are hundreds of scientists involved in British research projects which are funded by the EU.

The lead scientist on the autism project at Kings is Professor Declan Murphy - and he too is concerned about what Brexit will mean.

He says:"It's virtually impossible for one country alone to recruit the amount of patients that you really need for a large scale, modern day trial, or study that's going to lead to reliable results. We increasingly recognise that big questions need big populations to come up with the right answers and we simply cannot deliver the amount of patients for the amount of science from one centre from one country. For Example my work needs approximately a thousand individuals who are affected by autism. You couldn't recruit that from one centre, or from one country within a time frame that is meaningful, but we can do that by going to mulitple centres across Europe, working together and learning from eachother."

The EU's Horizon 2020 budget is 80-billion Euro which funds medicine and science research across Europe.

Britain's split from the EU will leave a funding gap as well as a brain drain according to Murphy and he argues it will be the children with autism who will lose out.

FOR CLEAN VERSION SEE STORY NUMBER: 4045006

LEAD IN:

Scientists controlling EU projects worth millions of dollars say the British exit from Europe risks the future of medical research, and may endanger future treatments for cancer and children.

Research projects at Kings and University Colleges in London rely on the collaboration of hundreds of doctors and multidisciplinary scientists across Europe - which could come under threat because of Brexit.

STORY-LINE:

Precision medicine is changing the future for cancer patients.

This lab at University College London has devised a safer and simpler alternative to standard radioactive techniques of imaging tumours.

Professor Xavier Golay's team has discovered a way to make a tumour light up with a simple sugar solution.

Because the solution is not radioactive is doesn't carry the same side effects which make patients sick.

It means radiodlogists can see tumours in more detail and check them more frequently.

That in turn allows doctors to personalise drug treatments for the patient.

They can respond more quickly, seeing what works and what doesn't and that speed could save more lives.

The team here is about to begin a trial on the new imaging technique thanks to a six and a half million Euro grant from the European Union.

The whole university has 103-million Euros to fund medical and science projects over the next few years.

All currently funded projects will be allowed to complete - but it's what happens next that's vexing doctors and scientist who argue breakthroughs don't come to order at the end of one trial.

Golay says for the vast majority of scientists in Britain the result of the recent EU referendum - for the UK to exit - was a shock.

Golay says it's not just the money which will risk future projects like this.

His team - like most university and hospital research groups - comes from all over the European Union.

Collaboration on this imaging project is with other specialist scientists at the Max Planck Institute in Germany as well as other units including France and Italy.

He's already concerned about the future.

"I've heard of at least two, three very senior people who've said okay right, now I'm taking all my grant with me and I'm going back to Germany, Switzerland, France because actually, in that way, they know they'll still have access and it's not only access to funding because the funding is great in this country, it is really good. It's really (about) access to funding and this opportunity to collaborate."

At preschool age Rens Van Velzen's parents realised he was struggling with dyslexia, but when he went to school it became clear he was autistic.

Van Velzen, now a highly intelligent fifteen year old, is part of Europe's largest study into mental health disorder.

Here researchers like Hannah Haywood combine genetics, neuroimaging, cognitive testing and clinical assessments to try to discover what are the causes.

The research project called EU Aims is carried out here at Kings College London in collaboration with scientists in other centres of Europe.

Costing 32 million Euros it's also the biggest grant given to any one project.

Autism Spectrum Disorder is a developmental problem which affects the way people interact with the world around them.

People are affected differently and scientists want to understand why those differences occur.

Haywood says: "One can go on to a life where they never speak, they are highly affected and quite disabled. Another person can go on (to be) fully verbal and become a professor at Cambridge (University) and someone else can go on and live a full life with marriage and children, why does that happen? Why does it affect people so differently when it's effectively the same condition. So we're trying to answer those questions, we're trying to understand why it affects different people in different ways and I think the thing that really attracted me to the project is because, we're trying to highlight the great skills and strengths in this group as well as the things that people find difficult."

The goal is to identify biomarkers and develop drug treatments.

It's a long term study, but how long can it continue here and what happens to the research after the current funding ends in 2020?

Rens Van Velzen is already preparing for A-levels in maths, chemistry and physics.

But his autism means life outside the classroom is not always straightforward.

He explains: "Quite often when talking peer to peer, the other person can get frustrated with how I respond because they're (I'm) not responding the way that they're expecting me to respond as the people usually do. So quite often I don't pick up someone's annoyed, or that sort of thing. It's very hard to explain because I haven't had the experience of not having autism."

Haywood, like others on the team, is convinced the project must be protected and fears Britain leaving the EU will end large scale endeavours like this which progress more steadily because of the wide collaboration among doctors and scientists.

She says: "Quite often there can be a lot of negativity around being diagnosed and living with the condition and in my work, I've worked with autism for twelve years, I have met some of the most skilled and highly intelligent people."

Van Velzen has been part of the study since it started.

Now he's hoping for a career in astrophysics.

"I think I'll work on either discovering more about our universe and our place in it, or working on ways to get to other parts of the universe," says Van Velzen.

After completing puzzles in record time he goes on for tests in the eye tracking unit.

Studies have used eye-tracing technology to see how long autistic children spend looking at the social and non-social features in a series of images on pictures and videos like these.

Ren's mother Jose Van Velzen is a cognitive neuroscientist herself although she does not work on this project.

While she is confident about her son's academic success she worries about how he will cope with work and whether he will find happiness in personal relationships.

She says: "It is sometimes challenging for Rens to keep track of what the person he's talking to is feeling and how he's being perceived. He's very much driven by telling things as they are, or how he sees them and of course in normal interaction, in normal relationships you constantly monitor what the other person is thinking. That's definitely very challenging for him and he is aware that this is one of his weaknesses he needs to work on he cannot always deal with it at that particular time and I think that is something in general that will make relationships and work environments quite a challenging place for him."

According to scientists here this project is the first of it kind in the world developing the infrastructure which will underpin new treatments for autism.

There are hundreds of scientists involved in British research projects which are funded by the EU.

The lead scientist on the autism project at Kings is Professor Declan Murphy - and he too is concerned about what Brexit will mean.

He says:"It's virtually impossible for one country alone to recruit the amount of patients that you really need for a large scale, modern day trial, or study that's going to lead to reliable results. We increasingly recognise that big questions need big populations to come up with the right answers and we simply cannot deliver the amount of patients for the amount of science from one centre from one country. For Example my work needs approximately a thousand individuals who are affected by autism. You couldn't recruit that from one centre, or from one country within a time frame that is meaningful, but we can do that by going to mulitple centres across Europe, working together and learning from eachother."

The EU's Horizon 2020 budget is 80-billion Euro which funds medicine and science research across Europe.

Britain's split from the EU will leave a funding gap as well as a brain drain according to Murphy and he argues it will be the children with autism who will lose out.

London, UK - 7 July 2016

1. Various CT scans showing liver cancer pre and post therapy to illustrate the relationship between tumours and glucose

2. Mid of Professor Xavier Golay looking at scans in his MRI lab at the UCL Institute of Neurology

3. Various of Golay and researcher looking at scans

4. Close of tumour in rat highlighted by non radioactive glucose

5. SOUNDBITE: (English) Xavier Golay, professor of neurophysics, UCL Institute of Neurology

"I've heard of at least two, three very senior people who've said okay right, now I'm taking all my grant with me and I'm going back to Germany, Switzerland, France because actually, in that way, they know they'll still have access and it's not only access to funding because the funding is great in this country, it is really good. It's really (about) access to funding and this opportunity to collaborate."

6. Close of autistic teenager Rens Van Velzen answering questions testing his cognitive and executive function at Kings College London

7. Close of psychologist Hannah Hayward asking questions

8. Mid of Velzen ticking off words he understands

9. Various of Velzen watching next task being set up

10. Mid of Velzen touching laptop screen to pick out the emotion displayed on the photo on the monitor

11. Close of Velzen touching the word "Cautious"

12. Close of touch screen

13. Mid of Velzen watching screen observed by Hayward

14. Close of Velzen

15. SOUNDBITE: (English) Hannah Hayward psychologist, EU Aims (autism research project) Kings College London

"One can go on to a life where they never speak, they are highly affected and quite disabled. Another person can go on (to be) fully verbal and become a professor at Cambridge (University) and someone else can go on and live a full life with marriage and children, why does that happen? Why does it affect people so differently when it's effectively the same condition? So we're trying to answer those questions, we're trying to understand why it affects different people in different ways and I think the thing that really attracted me to the project is because, we're trying to highlight the great skills and strengths in this group as well as the things that people find difficult."

16. Close of Hayward starting stopwatch

17. Close of cube pattern Velzen has to recreate

18. Close tilt down of Hayward observing

19. Close of Velzen

20. Close pan from pattern and blocks being constructed by Velzen

21. Mid of Velzen completing puzzle watched by Hayward

22. SOUNDBITE: (English) Rens Van Velzen, teenager in Kings College autisim research group

"Quite often when talking peer to peer, the other person can get frustrated with how I respond because they're (I'm) not responding the way that they're expecting me to respond as the people usually do. So quite often I don't pick up someone's annoyed, or that sort of thing. It's very hard to explain because I haven't had the experience of not having autism."

23. Various of Van Velzen completing other puzzles with black and yellow blocks

24. SOUNDBITE: (English) Hannah Hayward psychologist, EU Aims (autism research project) Kings College London

"Quite often there can be a lot of negativity around being diagnosed and living with the condition and in my work, I've worked with autism for twelve years, I have met some of the most skilled and highly intelligent people."

25. Various of Hayward attaching EEG wires to Van Velzen before eye tracking tests

26. SOUNDBITE: (English) Rens Van Velzen, teenager in Kings College autisim research group

"I think I'll work on either discovering more about our universe and our place in it, or working on ways to get to other parts of the universe."

27. Mid of monitor displaying photographs of facial expressions with options to pick the right description

28. Close of Van Velsen tapping keyboard

29. Mid of test continuing on monitor

30. SOUNDBITE: (English) Jose Van Velzen, Rens' mother (who is also a cognitive neuroscientist)

"It is sometimes challenging for Rens to keep track of what the person he's talking to is feeling and how he's being perceived. He's very much driven by telling things as they are, or how he sees them and of course in normal interaction, in normal relationships, you constantly monitor what the other person is thinking. That's definitely very challenging for him, and he is aware that this is one of his weaknesses he needs to work on he cannot always deal with it at that particular time and I think that is something in general that will make relationships and work environments quite a challenging place for him."

31. Mid rear view of Rens Van Velzen being shown photos in the eye tracking suite

32. Various of monitor

33. Various of Hayward carrying out tracking test

34. Hayward's monitor showing Rens Van Velzen responding to photographs

35. Mid rear view of Van Velzen watching animated patterns appear on screen

36. Various of Professor Declan Murphy lead scientist on the EU Aims study on autism

37. SOUNDBITE: (English) Professor Declan Murphy lead scientist, EU Aims study on autism, Kings College London

"It's virtually impossible for one country alone to recruit the amount of patients that you really need for a large scale, modern day trial, or study that's going to lead to reliable results. We increasingly recognise that big questions need big populations to come up with the right answers, and we simply cannot deliver the amount of patients for the amount of science from one centre from one country. For example, my work needs approximately a thousand individuals who are affected by autism. You couldn't recruit that from one centre, or from one country within a time frame that is meaningful, but we can do that by going to mulitple centres across Europe, working together and learning from eachother."

38. Mid rear view of Rens Van Velzen responding to picture during eyetracking test

39. Close of EEG reading on monitor

UK MEDICAL BREXIT

SOURCE: AP HORIZONS, LIFESTYLE, HEALTH AND TECHNOLOGY

RESTRICTIONS: HORIZONS CLIENTS AND AP LIFESTYLE, HEALTH AND TECHNOLOGY CLIENTS ONLY

LENGTH: 6.33

SHOTLIST:

London, UK - 7 July 2016

1. Various CT scans showing liver cancer pre and post therapy to illustrate the relationship between tumours and glucose

2. Mid of Professor Xavier Golay looking at scans in his MRI lab at the UCL Institute of Neurology

3. Various of Golay and researcher looking at scans

4. Close of tumour in rat highlighted by non radioactive glucose

5. SOUNDBITE: (English) Xavier Golay, professor of neurophysics, UCL Institute of Neurology

"I've heard of at least two, three very senior people who've said okay right, now I'm taking all my grant with me and I'm going back to Germany, Switzerland, France because actually, in that way, they know they'll still have access and it's not only access to funding because the funding is great in this country, it is really good. It's really (about) access to funding and this opportunity to collaborate."

6. Close of autistic teenager Rens Van Velzen answering questions testing his cognitive and executive function at Kings College London

7. Close of psychologist Hannah Hayward asking questions

8. Mid of Velzen ticking off words he understands

9. Various of Velzen watching next task being set up

10. Mid of Velzen touching laptop screen to pick out the emotion displayed on the photo on the monitor

11. Close of Velzen touching the word "Cautious"

12. Close of touch screen

13. Mid of Velzen watching screen observed by Hayward

14. Close of Velzen

15. SOUNDBITE: (English) Hannah Hayward psychologist, EU Aims (autism research project) Kings College London

"One can go on to a life where they never speak, they are highly affected and quite disabled. Another person can go on (to be) fully verbal and become a professor at Cambridge (University) and someone else can go on and live a full life with marriage and children, why does that happen? Why does it affect people so differently when it's effectively the same condition? So we're trying to answer those questions, we're trying to understand why it affects different people in different ways and I think the thing that really attracted me to the project is because, we're trying to highlight the great skills and strengths in this group as well as the things that people find difficult."

16. Close of Hayward starting stopwatch

17. Close of cube pattern Velzen has to recreate

18. Close tilt down of Hayward observing

19. Close of Velzen

20. Close pan from pattern and blocks being constructed by Velzen

21. Mid of Velzen completing puzzle watched by Hayward

22. SOUNDBITE: (English) Rens Van Velzen, teenager in Kings College autisim research group

"Quite often when talking peer to peer, the other person can get frustrated with how I respond because they're (I'm) not responding the way that they're expecting me to respond as the people usually do. So quite often I don't pick up someone's annoyed, or that sort of thing. It's very hard to explain because I haven't had the experience of not having autism."

23. Various of Van Velzen completing other puzzles with black and yellow blocks

24. SOUNDBITE: (English) Hannah Hayward psychologist, EU Aims (autism research project) Kings College London

"Quite often there can be a lot of negativity around being diagnosed and living with the condition and in my work, I've worked with autism for twelve years, I have met some of the most skilled and highly intelligent people."

25. Various of Hayward attaching EEG wires to Van Velzen before eye tracking tests

26. SOUNDBITE: (English) Rens Van Velzen, teenager in Kings College autisim research group

"I think I'll work on either discovering more about our universe and our place in it, or working on ways to get to other parts of the universe."

27. Mid of monitor displaying photographs of facial expressions with options to pick the right description

28. Close of Van Velsen tapping keyboard

29. Mid of test continuing on monitor

30. SOUNDBITE: (English) Jose Van Velzen, Rens' mother (who is also a cognitive neuroscientist)

"It is sometimes challenging for Rens to keep track of what the person he's talking to is feeling and how he's being perceived. He's very much driven by telling things as they are, or how he sees them and of course in normal interaction, in normal relationships, you constantly monitor what the other person is thinking. That's definitely very challenging for him, and he is aware that this is one of his weaknesses he needs to work on he cannot always deal with it at that particular time and I think that is something in general that will make relationships and work environments quite a challenging place for him."

31. Mid rear view of Rens Van Velzen being shown photos in the eye tracking suite

32. Various of monitor

33. Various of Hayward carrying out tracking test

34. Hayward's monitor showing Rens Van Velzen responding to photographs

35. Mid rear view of Van Velzen watching animated patterns appear on screen

36. Various of Professor Declan Murphy lead scientist on the EU Aims study on autism

37. SOUNDBITE: (English) Professor Declan Murphy lead scientist, EU Aims study on autism, Kings College London

"It's virtually impossible for one country alone to recruit the amount of patients that you really need for a large scale, modern day trial, or study that's going to lead to reliable results. We increasingly recognise that big questions need big populations to come up with the right answers, and we simply cannot deliver the amount of patients for the amount of science from one centre from one country. For example, my work needs approximately a thousand individuals who are affected by autism. You couldn't recruit that from one centre, or from one country within a time frame that is meaningful, but we can do that by going to mulitple centres across Europe, working together and learning from eachother."

38. Mid rear view of Rens Van Velzen responding to picture during eyetracking test

39. Close of EEG reading on monitor

LEADIN:

Scientists controlling EU projects worth millions of dollars say the British exit from Europe risks the future of medical research, and may endanger future treatments for cancer and children.

Research projects at Kings and University Colleges in London rely on the collaboration of hundreds of doctors and multidisciplinary scientists across Europe - which could come under threat because of Brexit.

STORYLINE:

Precision medicine is changing the future for cancer patients.

This lab at University College London has devised a safer and simpler alternative to standard radioactive techniques of imaging tumours.

Professor Xavier Golay's team has discovered a way to make a tumour light up with a simple sugar solution.

Because the solution is not radioactive is doesn't carry the same side effects which make patients sick.

It means radiodlogists can see tumours in more detail and check them more frequently.

That in turn allows doctors to personalise drug treatments for the patient.

They can respond more quickly, seeing what works and what doesn't and that speed could save more lives.

The team here is about to begin a trial on the new imaging technique thanks to a six and a half million Euro grant from the European Union.

The whole university has 103-million Euros to fund medical and science projects over the next few years.

All currently funded projects will be allowed to complete - but it's what happens next that's vexing doctors and scientist who argue breakthroughs don't come to order at the end of one trial.

Golay says for the vast majority of scientists in Britain the result of the recent EU referendum - for the UK to exit - was a shock.

Golay says it's not just the money which will risk future projects like this.

His team - like most university and hospital research groups - comes from all over the European Union.

Collaboration on this imaging project is with other specialist scientists at the Max Planck Institute in Germany as well as other units including France and Italy.

He's already concerned about the future.

"I've heard of at least two, three very senior people who've said okay right, now I'm taking all my grant with me and I'm going back to Germany, Switzerland, France because actually, in that way, they know they'll still have access and it's not only access to funding because the funding is great in this country, it is really good. It's really (about) access to funding and this opportunity to collaborate."

At preschool age Rens Van Velzen's parents realised he was struggling with dyslexia, but when he went to school it became clear he was autistic.

Van Velzen, now a highly intelligent fifteen year old, is part of Europe's largest study into mental health disorder.

Here researchers like Hannah Haywood combine genetics, neuroimaging, cognitive testing and clinical assessments to try to discover what are the causes.

The research project called EU Aims is carried out here at Kings College London in collaboration with scientists in other centres of Europe.

Costing 32 million Euros it's also the biggest grant given to any one project.

Autism Spectrum Disorder is a developmental problem which affects the way people interact with the world around them.

People are affected differently and scientists want to understand why those differences occur.

Haywood says: "One can go on to a life where they never speak, they are highly affected and quite disabled. Another person can go on (to be) fully verbal and become a professor at Cambridge (University) and someone else can go on and live a full life with marriage and children, why does that happen? Why does it affect people so differently when it's effectively the same condition. So we're trying to answer those questions, we're trying to understand why it affects different people in different ways and I think the thing that really attracted me to the project is because, we're trying to highlight the great skills and strengths in this group as well as the things that people find difficult."

The goal is to identify biomarkers and develop drug treatments.

It's a long term study, but how long can it continue here and what happens to the research after the current funding ends in 2020?

Rens Van Velzen is already preparing for A-levels in maths, chemistry and physics.

But his autism means life outside the classroom is not always straightforward.

He explains: "Quite often when talking peer to peer, the other person can get frustrated with how I respond because they're (I'm) not responding the way that they're expecting me to respond as the people usually do. So quite often I don't pick up someone's annoyed, or that sort of thing. It's very hard to explain because I haven't had the experience of not having autism."

Haywood, like others on the team, is convinced the project must be protected and fears Britain leaving the EU will end large scale endeavours like this which progress more steadily because of the wide collaboration among doctors and scientists.

She says: "Quite often there can be a lot of negativity around being diagnosed and living with the condition and in my work, I've worked with autism for twelve years, I have met some of the most skilled and highly intelligent people."

Van Velzen has been part of the study since it started.

Now he's hoping for a career in astrophysics.

"I think I'll work on either discovering more about our universe and our place in it, or working on ways to get to other parts of the universe," says Van Velzen.

After completing puzzles in record time he goes on for tests in the eye tracking unit.

Studies have used eye-tracing technology to see how long autistic children spend looking at the social and non-social features in a series of images on pictures and videos like these.

Ren's mother Jose Van Velzen is a cognitive neuroscientist herself although she does not work on this project.

While she is confident about her son's academic success she worries about how he will cope with work and whether he will find happiness in personal relationships.

She says: "It is sometimes challenging for Rens to keep track of what the person he's talking to is feeling and how he's being perceived. He's very much driven by telling things as they are, or how he sees them and of course in normal interaction, in normal relationships you constantly monitor what the other person is thinking. That's definitely very challenging for him and he is aware that this is one of his weaknesses he needs to work on he cannot always deal with it at that particular time and I think that is something in general that will make relationships and work environments quite a challenging place for him."

According to scientists here this project is the first of it kind in the world developing the infrastructure which will underpin new treatments for autism.

There are hundreds of scientists involved in British research projects which are funded by the EU.

The lead scientist on the autism project at Kings is Professor Declan Murphy - and he too is concerned about what Brexit will mean.

He says:"It's virtually impossible for one country alone to recruit the amount of patients that you really need for a large scale, modern day trial, or study that's going to lead to reliable results. We increasingly recognise that big questions need big populations to come up with the right answers and we simply cannot deliver the amount of patients for the amount of science from one centre from one country. For Example my work needs approximately a thousand individuals who are affected by autism. You couldn't recruit that from one centre, or from one country within a time frame that is meaningful, but we can do that by going to mulitple centres across Europe, working together and learning from each other."

The EU's Horizon 2020 budget is 80-billion Euro which funds medicine and science research across Europe.

Britain's split from the EU will leave a funding gap as well as a brain drain according to Murphy and he argues it will be the children with autism who will lose out.

====

Clients are reminded:

(i) to check the terms of their licence agreements for use of content outside news programming and that further advice and assistance can be obtained from the AP Archive on: Tel +44 (0) 20 7482 7482 Email: info@aparchive.com.

(ii) they should check with the applicable collecting society in their Territory regarding the clearance of any sound recording or performance included within the AP Television News service

(iii) they have editorial responsibility for the use of all and any content included within the AP Television News service and for libel, privacy, compliance and third party rights applicable to their Territory.

UK MEDICAL BREXIT

SOURCE: AP TECHNOLOGY

RESTRICTIONS: TECHNOLOGY CLIENTS ONLY

LENGTH: 6.33

SHOTLIST:

London, UK - 7 July 2016

1. Various CT scans showing liver cancer pre and post therapy to illustrate the relationship between tumours and glucose

2. Mid of Professor Xavier Golay looking at scans in his MRI lab at the UCL Institute of Neurology

3. Various of Golay and researcher looking at scans

4. Close of tumour in rat highlighted by non radioactive glucose

5. SOUNDBITE: (English) Xavier Golay, professor of neurophysics, UCL Institute of Neurology

"I've heard of at least two, three very senior people who've said okay right, now I'm taking all my grant with me and I'm going back to Germany, Switzerland, France because actually, in that way, they know they'll still have access and it's not only access to funding because the funding is great in this country, it is really good. It's really (about) access to funding and this opportunity to collaborate."

6. Close of autistic teenager Rens Van Velzen answering questions testing his cognitive and executive function at Kings College London

7. Close of psychologist Hannah Hayward asking questions

8. Mid of Velzen ticking off words he understands

9. Various of Velzen watching next task being set up

10. Mid of Velzen touching laptop screen to pick out the emotion displayed on the photo on the monitor

11. Close of Velzen touching the word "Cautious"

12. Close of touch screen

13. Mid of Velzen watching screen observed by Hayward

14. Close of Velzen

15. SOUNDBITE: (English) Hannah Hayward psychologist, EU Aims (autism research project) Kings College London

"One can go on to a life where they never speak, they are highly affected and quite disabled. Another person can go on (to be) fully verbal and become a professor at Cambridge (University) and someone else can go on and live a full life with marriage and children, why does that happen? Why does it affect people so differently when it's effectively the same condition? So we're trying to answer those questions, we're trying to understand why it affects different people in different ways and I think the thing that really attracted me to the project is because, we're trying to highlight the great skills and strengths in this group as well as the things that people find difficult."

16. Close of Hayward starting stopwatch

17. Close of cube pattern Velzen has to recreate

18. Close tilt down of Hayward observing

19. Close of Velzen

20. Close pan from pattern and blocks being constructed by Velzen

21. Mid of Velzen completing puzzle watched by Hayward

22. SOUNDBITE: (English) Rens Van Velzen, teenager in Kings College autisim research group

"Quite often when talking peer to peer, the other person can get frustrated with how I respond because they're (I'm) not responding the way that they're expecting me to respond as the people usually do. So quite often I don't pick up someone's annoyed, or that sort of thing. It's very hard to explain because I haven't had the experience of not having autism."

23. Various of Van Velzen completing other puzzles with black and yellow blocks

24. SOUNDBITE: (English) Hannah Hayward psychologist, EU Aims (autism research project) Kings College London

"Quite often there can be a lot of negativity around being diagnosed and living with the condition and in my work, I've worked with autism for twelve years, I have met some of the most skilled and highly intelligent people."

25. Various of Hayward attaching EEG wires to Van Velzen before eye tracking tests

26. SOUNDBITE: (English) Rens Van Velzen, teenager in Kings College autisim research group

"I think I'll work on either discovering more about our universe and our place in it, or working on ways to get to other parts of the universe."

27. Mid of monitor displaying photographs of facial expressions with options to pick the right description

28. Close of Van Velsen tapping keyboard

29. Mid of test continuing on monitor

30. SOUNDBITE: (English) Jose Van Velzen, Rens' mother (who is also a cognitive neuroscientist)

"It is sometimes challenging for Rens to keep track of what the person he's talking to is feeling and how he's being perceived. He's very much driven by telling things as they are, or how he sees them and of course in normal interaction, in normal relationships, you constantly monitor what the other person is thinking. That's definitely very challenging for him, and he is aware that this is one of his weaknesses he needs to work on he cannot always deal with it at that particular time and I think that is something in general that will make relationships and work environments quite a challenging place for him."

31. Mid rear view of Rens Van Velzen being shown photos in the eye tracking suite

32. Various of monitor

33. Various of Hayward carrying out tracking test

34. Hayward's monitor showing Rens Van Velzen responding to photographs

35. Mid rear view of Van Velzen watching animated patterns appear on screen

36. Various of Professor Declan Murphy lead scientist on the EU Aims study on autism

37. SOUNDBITE: (English) Professor Declan Murphy lead scientist, EU Aims study on autism, Kings College London

"It's virtually impossible for one country alone to recruit the amount of patients that you really need for a large scale, modern day trial, or study that's going to lead to reliable results. We increasingly recognise that big questions need big populations to come up with the right answers, and we simply cannot deliver the amount of patients for the amount of science from one centre from one country. For example, my work needs approximately a thousand individuals who are affected by autism. You couldn't recruit that from one centre, or from one country within a time frame that is meaningful, but we can do that by going to mulitple centres across Europe, working together and learning from eachother."

38. Mid rear view of Rens Van Velzen responding to picture during eyetracking test

39. Close of EEG reading on monitor

LEADIN:

Scientists controlling EU projects worth millions of dollars say the British exit from Europe risks the future of medical research, and may endanger future treatments for cancer and children.

Research projects at Kings and University Colleges in London rely on the collaboration of hundreds of doctors and multidisciplinary scientists across Europe - which could come under threat because of Brexit.

STORYLINE:

Precision medicine is changing the future for cancer patients.

This lab at University College London has devised a safer and simpler alternative to standard radioactive techniques of imaging tumours.

Professor Xavier Golay's team has discovered a way to make a tumour light up with a simple sugar solution.

Because the solution is not radioactive is doesn't carry the same side effects which make patients sick.

It means radiodlogists can see tumours in more detail and check them more frequently.

That in turn allows doctors to personalise drug treatments for the patient.

They can respond more quickly, seeing what works and what doesn't and that speed could save more lives.

The team here is about to begin a trial on the new imaging technique thanks to a six and a half million Euro grant from the European Union.

The whole university has 103-million Euros to fund medical and science projects over the next few years.

All currently funded projects will be allowed to complete - but it's what happens next that's vexing doctors and scientist who argue breakthroughs don't come to order at the end of one trial.

Golay says for the vast majority of scientists in Britain the result of the recent EU referendum - for the UK to exit - was a shock.

Golay says it's not just the money which will risk future projects like this.

His team - like most university and hospital research groups - comes from all over the European Union.

Collaboration on this imaging project is with other specialist scientists at the Max Planck Institute in Germany as well as other units including France and Italy.

He's already concerned about the future.

"I've heard of at least two, three very senior people who've said okay right, now I'm taking all my grant with me and I'm going back to Germany, Switzerland, France because actually, in that way, they know they'll still have access and it's not only access to funding because the funding is great in this country, it is really good. It's really (about) access to funding and this opportunity to collaborate."

At preschool age Rens Van Velzen's parents realised he was struggling with dyslexia, but when he went to school it became clear he was autistic.

Van Velzen, now a highly intelligent fifteen year old, is part of Europe's largest study into mental health disorder.

Here researchers like Hannah Haywood combine genetics, neuroimaging, cognitive testing and clinical assessments to try to discover what are the causes.

The research project called EU Aims is carried out here at Kings College London in collaboration with scientists in other centres of Europe.

Costing 32 million Euros it's also the biggest grant given to any one project.

Autism Spectrum Disorder is a developmental problem which affects the way people interact with the world around them.

People are affected differently and scientists want to understand why those differences occur.

Haywood says: "One can go on to a life where they never speak, they are highly affected and quite disabled. Another person can go on (to be) fully verbal and become a professor at Cambridge (University) and someone else can go on and live a full life with marriage and children, why does that happen? Why does it affect people so differently when it's effectively the same condition. So we're trying to answer those questions, we're trying to understand why it affects different people in different ways and I think the thing that really attracted me to the project is because, we're trying to highlight the great skills and strengths in this group as well as the things that people find difficult."

The goal is to identify biomarkers and develop drug treatments.

It's a long term study, but how long can it continue here and what happens to the research after the current funding ends in 2020?

Rens Van Velzen is already preparing for A-levels in maths, chemistry and physics.

But his autism means life outside the classroom is not always straightforward.

He explains: "Quite often when talking peer to peer, the other person can get frustrated with how I respond because they're (I'm) not responding the way that they're expecting me to respond as the people usually do. So quite often I don't pick up someone's annoyed, or that sort of thing. It's very hard to explain because I haven't had the experience of not having autism."

Haywood, like others on the team, is convinced the project must be protected and fears Britain leaving the EU will end large scale endeavours like this which progress more steadily because of the wide collaboration among doctors and scientists.

She says: "Quite often there can be a lot of negativity around being diagnosed and living with the condition and in my work, I've worked with autism for twelve years, I have met some of the most skilled and highly intelligent people."

Van Velzen has been part of the study since it started.

Now he's hoping for a career in astrophysics.

"I think I'll work on either discovering more about our universe and our place in it, or working on ways to get to other parts of the universe," says Van Velzen.

After completing puzzles in record time he goes on for tests in the eye tracking unit.

Studies have used eye-tracing technology to see how long autistic children spend looking at the social and non-social features in a series of images on pictures and videos like these.

Ren's mother Jose Van Velzen is a cognitive neuroscientist herself although she does not work on this project.

While she is confident about her son's academic success she worries about how he will cope with work and whether he will find happiness in personal relationships.

She says: "It is sometimes challenging for Rens to keep track of what the person he's talking to is feeling and how he's being perceived. He's very much driven by telling things as they are, or how he sees them and of course in normal interaction, in normal relationships you constantly monitor what the other person is thinking. That's definitely very challenging for him and he is aware that this is one of his weaknesses he needs to work on he cannot always deal with it at that particular time and I think that is something in general that will make relationships and work environments quite a challenging place for him."

According to scientists here this project is the first of it kind in the world developing the infrastructure which will underpin new treatments for autism.

There are hundreds of scientists involved in British research projects which are funded by the EU.

The lead scientist on the autism project at Kings is Professor Declan Murphy - and he too is concerned about what Brexit will mean.

He says:"It's virtually impossible for one country alone to recruit the amount of patients that you really need for a large scale, modern day trial, or study that's going to lead to reliable results. We increasingly recognise that big questions need big populations to come up with the right answers and we simply cannot deliver the amount of patients for the amount of science from one centre from one country. For Example my work needs approximately a thousand individuals who are affected by autism. You couldn't recruit that from one centre, or from one country within a time frame that is meaningful, but we can do that by going to mulitple centres across Europe, working together and learning from each other."

The EU's Horizon 2020 budget is 80-billion Euro which funds medicine and science research across Europe.

Britain's split from the EU will leave a funding gap as well as a brain drain according to Murphy and he argues it will be the children with autism who will lose out.

====

Clients are reminded:

(i) to check the terms of their licence agreements for use of content outside news programming and that further advice and assistance can be obtained from the AP Archive on: Tel +44 (0) 20 7482 7482 Email: info@aparchive.com.

(ii) they should check with the applicable collecting society in their Territory regarding the clearance of any sound recording or performance included within the AP Television News service

(iii) they have editorial responsibility for the use of all and any content included within the AP Television News service and for libel, privacy, compliance and third party rights applicable to their Territory.

UK TOYS

SOURCE: AP HORIZONS, LIFESTYLE, HEALTH AND TECHNOLOGY

RESTRICTIONS: HORIZONS CLIENTS AND AP LIFESTYLE, HEALTH AND TECHNOLOGY CLIENTS ONLY

LENGTH: 6.02

SHOTLIST:

London, UK - 9 November 2016

1. Close tilt up of Hatchimals egg box the most popular toy

2. Mid of Tiana Wilson with Santa who is holding a Hatchimal waiting for the toy to hatch

3. Various of Tiana Wilson and Santa Claus listening to toy hatch

4. Close of egg showing beak poking through eggshell

5. Close of Santa Claus watching

6. Various of Santa and Wilson releasing the hatching toy

7. Close of Wilson listening to the Hatchimal sing Happy Birthday

8. SOUNDBITE: (English) Tiana Wilson:

"So it can walk and then it sings Happy Birthday sometimes as well and then the eyes light up in different moods and stuff."

9. SOUNDBITE: (English) Gary Grant, retailer, Chairman, Dream Toys selection committee:

"In all the years I've been selling toys, you know we've chased around Tracy Island, we've chased around Care Bears and Cabbage Patch Kids, but this seems to be just gone to another level and the thing is about Hatchimal, it comes as an egg, by nurturing it and keeping it warm the chick inside the egg starts to become warm, starts to become alive, starts to make noises and after a while it starts to spin around inside the egg and it starts pecking and it starts to break the egg open and then literally you hatch the egg."

10. Mid of Hatchimal on the floor being stroked

11. Various of packaged Hatchimals

12. SOUNDBITE: (English) Gary Grant, retailer, Chairman, Dream Toys selection committee:

"Something that's really disappointing for me as a parent and as a grandparent is that you've got the speculators involved. You've got people that are buying them when they can and putting back onto a number of the internet channels at nearly double the price, so parents who are desperate to get the toy they want for their own children are buying them from people who never wanted them, they only bought them because they wanted to make money on them, it's really disappointing, but this is going on throughout the world, it's happening in Canada, it's happening in the (United) States, it's happening in the UK, just everybody's chasing around for Hatchimals this Christmas."

13. Mid of boy playing with toy gun

14. Close tilt down of girl playing with the new Bluetooth connected Furby which responds to what she does with her smartphone, or tablet computer

15. Wide of woman showing girl how the new Furby works

16. Low wide angle of the girl tickling the Furby toy

17. Pan from Christmas tree to wide of girl walking her toy dog on a lead

18. Close of toy dog on a lead walking

19. Mid zoom out of a girl seated cuddling an interactive puppy

20. Mid zoom in to boys playing with Bluetooth Furbys

21. Low mid view of caterpillar going past boys and Furbys

22. Zoom out from wrapped Christmas presents in giant sack to reveal Santa Claus walking with analyst Frederique Tutt

23. SOUNDBITE: (English) Frederique Tutt, toy industry analyst, NPD:

"Just like Brexit in June we've seen the election hasn't actually traumatised the UK market at all, so since the Brexit vote the toy market has been faring really well with an increase of three percent."

24. Tracking shot past model wearing costume of Silly Sausage to boy and girl playing Silly Sausage

25. Various of Silly Sausage toys being played

26. Wide of new range of Barbie dolls

27. Close tilt up of one of the new 'curvy' Barbie

28. Close tilt down from new afro Caribbean Barbie

29. Various of Barbies

30. SOUNDBITE: (English) Frederique Tutt, toy industry analyst, NPD:

"Probably ten percent. If we had to put a figure I would say there is a risk toys can increase by ten percent (in 2017)."

31. Close of bendy and stretchy muscle man toy

32. UPSOUND: (English) voice of Darth Vader from Star Wars over tilt up shot of Vader model

"Release your anger. If you only knew the power of the dark side."

33. Wide of Darth Vader model

34. Various of children playing with dog in a bath toy

35. SOUNDBITE: (English) Gary Grant, retailer, Chairman, Dream Toys selection committee:

"Many decisions that people are considering are on pause until we know the outcome of some of the discussions that are taking place about free passage of goods, movement of people and so on."

36. Zoom in of boy stroking interactive puppy

LEADIN:

Retailers in the UK have just revealed their top twelve 'must have' toys for boys and girls this Christmas.

The toy industry is predicting bumper sales, although it admits the US election of Donald Trump and Britain's EU exit vote earlier this year could lead to higher prices in 2017.

STORYLINE:

This is the toy everyone is raving about in the run up to Christmas.

Hatchimals respond to nurturing and warmth until eventually the egg cracks open and you have a new chick to take care of.

It's one of twelve toys which have made it to the list of Dream Toys which are selected each year by the industry.

Santa Claus and school girl Tiana Wilson are clearly fascinated and the excitement builds up as the chick starts hatching.

Wilson happily lists the toys attractions: "So it can walk and then it sings Happy Birthday sometimes as well and then the eyes light up in different moods and stuff."

A lot of interactive, or responsive toys like Hatchimals are most popular this winter, although the old favourites like Thomas the Tank Engine and Lego have secured places on the top toy list.

Toys like Furby have been updated with new technology so they are connected to computers via bluetooth.

Gary Grant the chairman of Dream Toys' selection committee says: "In all the years I've been selling toys, you know we've chased around Tracy Island, we've chased around Care Bears and Cabbage Patch Kids, but this seems to be just gone to another level and the thing is about Hatchimal, it comes as an egg, by nurturing it and keeping it warm the chick inside the egg starts to become warm, starts to become alive, starts to make noises and after a while it starts to spin around inside the egg and it starts pecking and it starts to break the egg open and then literally you hatch the egg."

Securing a Hatchimal this year might be tricky. According to Grant, there is already a worldwide shortage of the toy because the factory can't make enough of them.

Globally the demand for the Hatchimal is over a quarter of a million units, and the company expects to sell over 100,000 toys at around £60 each.

Grant says the shortage has meant some people are buying them to resell at a profit.

He says: "Something that's really disappointing for me as a parent and as a grandparent is that you've got the speculators involved. You've got people that are buying them when they can and putting back onto a number of the internet channels at nearly double the price, so parents who are desperate to get the toy they want for their own children are buying them from people who never wanted them, they only bought them because they wanted to make money on them, it's really disappointing, but this is going on throughout the world, it's happening in Canada, it's happening in the (United) States, it's happening in the UK, just everybody's chasing around for Hatchimals this Christmas."

One of the less expensive toys making the list this year is the Silly Sausage which tests your dexterity.

This is the new Barbie range developed to reflect the diversity in our societies.

The shape of the dolls is less extreme and more in keeping with natural proportions of young women.

There is even a 'curvy' Barbie, but you have to look closely to tell the difference between them.

There is a great deal of trepidation in the industry.

Analysts say 2015 was a record year with the global market valued at 86 billion dollars with an average growth of 7% across all the major markets.

But the US election and Britain's withdrawal from the EU is creating a great deal of uncertainty, over currency values and more importantly the security of existing trade deals.

Frederique Tutt, a global analyst who's a specialist on the toy industry says we shouldn't assume that it's going to be a gloomy future.

Tutt says: "Just like Brexit in June we've seen the election hasn't actually traumatised the UK market at all, so since the Brexit vote the toy market has been faring really well with an increase of three percent."

Toy retailers operate many months ahead so Tutt says there won't be price rises this year.

This is because trading is done in US dollars and most companies will have already stocked up on the currency to hedge against any drastic changes.

Tutt however admits price increases are likely next year and she says: "Probably ten percent. If we had to put a figure I would say there is a risk toys can rise by ten percent (in 2017)."

This Darth Vader is more of an adult toy.

Hidden sensors mean he can call out when you least expect him to.

Although there's the same old excitement about the approach of the winter holidays and the biggest gift buying time of the year, the industry is concerned about what lies ahead.

Grant says: "Many decisions that people are considering are on pause until we know the outcome of some of the discussions that are taking place about free passage of goods, movement of people and so on."

They say a puppy isn't just for Christmas, but sometimes they are.

====

Clients are reminded:

(i) to check the terms of their licence agreements for use of content outside news programming and that further advice and assistance can be obtained from the AP Archive on: Tel +44 (0) 20 7482 7482 Email: info@aparchive.com.

(ii) they should check with the applicable collecting society in their Territory regarding the clearance of any sound recording or performance included within the AP Television News service

(iii) they have editorial responsibility for the use of all and any content included within the AP Television News service and for libel, privacy, compliance and third party rights applicable to their Territory.

FOR CLEAN VERSION SEE STORY NUMBER: 4043378

LEAD IN:

Science research and development in the UK may face an uncertain future following last week's Brexit decision, but that isn't stopping the UK's top robotics companies.

They've been showing off their latest flying, shape-shifting – and in some cases potentially life changing – inventions at Britain's first Robotics Week.

STORY-LINE:

From shape-changing robots to dexterous mechanical arms, the latest in robotics was on show at the UK's first ever Robotics Week.

The event, from the 25 June to the 1 July, aims to get the British public engaged with developments and debates around robotics.

This shape-shifting robot is designed to manoeuvre over a variety of terrains to access hard to reach places, making it useful in the aftermath of a natural disaster.

But, taking place just days after the seismic political shift caused by the Brexit referendum, the impact of leaving the European Union was also at the forefront of people's minds.

Around 18.3 per cent of the funds the UK receives from the EU goes towards funding scientific research and development, a House of Lords committee said recently.

But Paul Newman, BP Professor of Information Engineering at the University of Oxford, says the UK's scientific community will continue to cooperate with others around the world whatever happens.

"Science doesn't respect national borders, we're part of a global community" he says.

While fans of the Terminator films may fear the rise of the robots, exhibitors at the event were keen to show how robotics can protect people.

The Shadow Dextrous Hand, made by the Shadow Robot Company, can be used for situations such as bomb disposal.

Armando De La Rosa, head of dexterous manipulation at Shadow Robot Company, says: "If you think of in bomb disposal and nuclear commissioning, this is often where you need human dexterity but you don't want a human nearby. This can be attached to a robot arm, to a little rover, and send it on its way and you have the operator somewhere else, at a safe distance, being able to remotely operate the hand to do whatever needs doing and if something goes wrong the operator is at no risk."

De La Rosa thinks that robotics are not just science fiction, but increasingly part of daily life.

"Robots are just going everywhere, in our homes, into space, into industry so the dream is not just in space but just robots everywhere making everybody's life better," he says.

While the Shadow Dextrous Hand is currently too heavy to be used as a prosthetic, other artificial limbs were on show.

Basingstoke-based company Blatchford demonstrated its Linx Limb, which it claims is the most advanced prosthetic limb in the world.

It was the recent winner of the UK's leading prize for innovation in engineering, the MacRobert Award from the Royal Academy of Engineering.

Dr Saeed Zahedi, technical director at Blatchford, explains: "This is the first integrated limb where the ankle and knee, they talk to each other, and behave in a coordinated manner."

"So for example if the amputee is going down the slope it would provide a break at the ankle as well as a break at the knee. An array of sensors at the knee and the ankle, they provide the information to each other so it can coordinate and synchronise and predict what the person is going to do in the same manner as you and I will go down the slope or go up the slope or go down the stairs or stand. Therefore the effort an amputee has to put into walking a leg will reduce," he says.

This exhibit shows how drones, dexterous digits and smart prosthetics are changing our future and bringing hi tech into our every day lives.

FOR CLEAN VERSION SEE STORY NUMBER: 4043378

LEAD IN:

Science research and development in the UK may face an uncertain future following last week's Brexit decision, but that isn't stopping the UK's top robotics companies.

They've been showing off their latest flying, shape-shifting – and in some cases potentially life changing – inventions at Britain's first Robotics Week.

STORY-LINE:

From shape-changing robots to dexterous mechanical arms, the latest in robotics was on show at the UK's first ever Robotics Week.

The event, from the 25 June to the 1 July, aims to get the British public engaged with developments and debates around robotics.

This shape-shifting robot is designed to manoeuvre over a variety of terrains to access hard to reach places, making it useful in the aftermath of a natural disaster.

But, taking place just days after the seismic political shift caused by the Brexit referendum, the impact of leaving the European Union was also at the forefront of people's minds.

Around 18.3 per cent of the funds the UK receives from the EU goes towards funding scientific research and development, a House of Lords committee said recently.

But Paul Newman, BP Professor of Information Engineering at the University of Oxford, says the UK's scientific community will continue to cooperate with others around the world whatever happens.

"Science doesn't respect national borders, we're part of a global community" he says.

While fans of the Terminator films may fear the rise of the robots, exhibitors at the event were keen to show how robotics can protect people.

The Shadow Dextrous Hand, made by the Shadow Robot Company, can be used for situations such as bomb disposal.

Armando De La Rosa, head of dexterous manipulation at Shadow Robot Company, says: "If you think of in bomb disposal and nuclear commissioning, this is often where you need human dexterity but you don't want a human nearby. This can be attached to a robot arm, to a little rover, and send it on its way and you have the operator somewhere else, at a safe distance, being able to remotely operate the hand to do whatever needs doing and if something goes wrong the operator is at no risk."

De La Rosa thinks that robotics are not just science fiction, but increasingly part of daily life.

"Robots are just going everywhere, in our homes, into space, into industry so the dream is not just in space but just robots everywhere making everybody's life better," he says.

While the Shadow Dextrous Hand is currently too heavy to be used as a prosthetic, other artificial limbs were on show.

Basingstoke-based company Blatchford demonstrated its Linx Limb, which it claims is the most advanced prosthetic limb in the world.

It was the recent winner of the UK's leading prize for innovation in engineering, the MacRobert Award from the Royal Academy of Engineering.

Dr Saeed Zahedi, technical director at Blatchford, explains: "This is the first integrated limb where the ankle and knee, they talk to each other, and behave in a coordinated manner."

"So for example if the amputee is going down the slope it would provide a break at the ankle as well as a break at the knee. An array of sensors at the knee and the ankle, they provide the information to each other so it can coordinate and synchronise and predict what the person is going to do in the same manner as you and I will go down the slope or go up the slope or go down the stairs or stand. Therefore the effort an amputee has to put into walking a leg will reduce," he says.

This exhibit shows how drones, dexterous digits and smart prosthetics are changing our future and bringing hi tech into our every day lives.

London - 1 July 2016

1. Various of shape changing robot walking and waving.

2. Various of Paul Newman, BP Professor of Information Engineering at the University of Oxford, looking at a display in the IET.

3. SOUNDBITE (English): Paul Newman, BP Professor of Information Engineering at the University of Oxford:

"Science doesn't respect national borders. So, we're part of a global community"

4. Various of Shadow Dextrous Hand being operated by Armando De La Rosa, head of dexterous manipulation at the Shadow Robot Company.

5. SOUNDBITE (English) Armando De La Rosa, head of dexterous manipulation at the Shadow Robot Company:

"Especially for dangerous environments where often you need - if you think of in bomb disposal and nuclear commissioning, this is often where you need human dexterity but you don't want a human nearby. This can be attached to a robot arm, to a little rover, and send it on its way and you have the operator somewhere else, at a safe distance, being able to remotely operate the hand to do whatever needs doing and if something goes wrong the operator is at no risk."

6. Various of Shadow Dextrous Hand being operated by Armando De La Rosa, head of dexterous manipulation at the Shadow Robot Company.

7. SOUNDBITE (English) Armando De La Rosa, head of dexterous manipulation at the Shadow Robot Company:

"Robots are just going everywhere, in our homes, into space, into industry so the dream is not just in space but just robots everywhere making everybody's life better."

8. Various of visitors looking at exhibits at the UK Robotics Week event

9. Various of Dr Saeed Zahedi, technical director at Blatchford, with the Linx Limb.

10. SOUNDBITE (English): Dr Saeed Zahedi, technical director at Blatchford.

"This is the first integrated limb where the ankle and knee, they talk to each other, and behave in a coordinated manner. So for example if the amputee is going down the slope it would provide a break at the ankle as well as a break at the knee. An array of sensors at the knee and the ankle, they provide the information to each other so it can coordinate and synchronise and predict what the person is going to do in the same manner as you and I will go down the slope or go up the slope or go down the stairs or stand. Therefore the effort an amputee has to put into walking a leg will reduce."

11. Various of robotics on display at the UK Robotics Week event.

LEAD IN:

Science research and development in the UK may face an uncertain future following last week's Brexit decision, but that isn't stopping the UK's top robotics companies.

They've been showing off their latest flying, shape-shifting – and in some cases potentially life changing – inventions at Britain's first Robotics Week.

STORY-LINE:

From shape-changing robots to dexterous mechanical arms, the latest in robotics was on show at the UK's first ever Robotics Week.

The event, from the 25 June to the 1 July, aims to get the British public engaged with developments and debates around robotics.

This shape-shifting robot is designed to manoeuvre over a variety of terrains to access hard to reach places, making it useful in the aftermath of a natural disaster.

But, taking place just days after the seismic political shift caused by the Brexit referendum, the impact of leaving the European Union was also at the forefront of people's minds.

Around 18.3 per cent of the funds the UK receives from the EU goes towards funding scientific research and development, a House of Lords committee said recently.

But Paul Newman, BP Professor of Information Engineering at the University of Oxford, says the UK's scientific community will continue to cooperate with others around the world whatever happens.

"Science doesn't respect national borders, we're part of a global community" he says.

While fans of the Terminator films may fear the rise of the robots, exhibitors at the event were keen to show how robotics can protect people.

The Shadow Dextrous Hand, made by the Shadow Robot Company, can be used for situations such as bomb disposal.

Armando De La Rosa, head of dexterous manipulation at Shadow Robot Company, says: "If you think of in bomb disposal and nuclear commissioning, this is often where you need human dexterity but you don't want a human nearby. This can be attached to a robot arm, to a little rover, and send it on its way and you have the operator somewhere else, at a safe distance, being able to remotely operate the hand to do whatever needs doing and if something goes wrong the operator is at no risk."

De La Rosa thinks that robotics are not just science fiction, but increasingly part of daily life.

"Robots are just going everywhere, in our homes, into space, into industry so the dream is not just in space but just robots everywhere making everybody's life better," he says.

While the Shadow Dextrous Hand is currently too heavy to be used as a prosthetic, other artificial limbs were on show.

Basingstoke-based company Blatchford demonstrated its Linx Limb, which it claims is the most advanced prosthetic limb in the world.

It was the recent winner of the UK's leading prize for innovation in engineering, the MacRobert Award from the Royal Academy of Engineering.

Dr Saeed Zahedi, technical director at Blatchford, explains: "This is the first integrated limb where the ankle and knee, they talk to each other, and behave in a coordinated manner."

"So for example if the amputee is going down the slope it would provide a break at the ankle as well as a break at the knee. An array of sensors at the knee and the ankle, they provide the information to each other so it can coordinate and synchronise and predict what the person is going to do in the same manner as you and I will go down the slope or go up the slope or go down the stairs or stand. Therefore the effort an amputee has to put into walking a leg will reduce," he says.

This exhibit shows how drones, dexterous digits and smart prosthetics are changing our future and bringing hi tech into our every day lives.

LEAD IN:

Science research and development in the UK may face an uncertain future following last week's Brexit decision, but that isn't stopping the UK's top robotics companies.

They've been showing off their latest flying, shape-shifting – and in some cases potentially life changing – inventions at Britain's first Robotics Week.

STORY-LINE:

From shape-changing robots to dexterous mechanical arms, the latest in robotics was on show at the UK's first ever Robotics Week.

The event, from the 25 June to the 1 July, aims to get the British public engaged with developments and debates around robotics.

This shape-shifting robot is designed to manoeuvre over a variety of terrains to access hard to reach places, making it useful in the aftermath of a natural disaster.

But, taking place just days after the seismic political shift caused by the Brexit referendum, the impact of leaving the European Union was also at the forefront of people's minds.

Around 18.3 per cent of the funds the UK receives from the EU goes towards funding scientific research and development, a House of Lords committee said recently.

But Paul Newman, BP Professor of Information Engineering at the University of Oxford, says the UK's scientific community will continue to cooperate with others around the world whatever happens.

"Science doesn't respect national borders, we're part of a global community" he says.

While fans of the Terminator films may fear the rise of the robots, exhibitors at the event were keen to show how robotics can protect people.

The Shadow Dextrous Hand, made by the Shadow Robot Company, can be used for situations such as bomb disposal.

Armando De La Rosa, head of dexterous manipulation at Shadow Robot Company, says: "If you think of in bomb disposal and nuclear commissioning, this is often where you need human dexterity but you don't want a human nearby. This can be attached to a robot arm, to a little rover, and send it on its way and you have the operator somewhere else, at a safe distance, being able to remotely operate the hand to do whatever needs doing and if something goes wrong the operator is at no risk."

De La Rosa thinks that robotics are not just science fiction, but increasingly part of daily life.

"Robots are just going everywhere, in our homes, into space, into industry so the dream is not just in space but just robots everywhere making everybody's life better," he says.

While the Shadow Dextrous Hand is currently too heavy to be used as a prosthetic, other artificial limbs were on show.

Basingstoke-based company Blatchford demonstrated its Linx Limb, which it claims is the most advanced prosthetic limb in the world.

It was the recent winner of the UK's leading prize for innovation in engineering, the MacRobert Award from the Royal Academy of Engineering.

Dr Saeed Zahedi, technical director at Blatchford, explains: "This is the first integrated limb where the ankle and knee, they talk to each other, and behave in a coordinated manner."

"So for example if the amputee is going down the slope it would provide a break at the ankle as well as a break at the knee. An array of sensors at the knee and the ankle, they provide the information to each other so it can coordinate and synchronise and predict what the person is going to do in the same manner as you and I will go down the slope or go up the slope or go down the stairs or stand. Therefore the effort an amputee has to put into walking a leg will reduce," he says.

This exhibit shows how drones, dexterous digits and smart prosthetics are changing our future and bringing hi tech into our every day lives.

London - 1 July 2016

1. Various of shape changing robot walking and waving.

2. Various of Paul Newman, BP Professor of Information Engineering at the University of Oxford, looking at a display in the IET.

3. SOUNDBITE (English): Paul Newman, BP Professor of Information Engineering at the University of Oxford:

"Science doesn't respect national borders. So, we're part of a global community"

4. Various of Shadow Dextrous Hand being operated by Armando De La Rosa, head of dexterous manipulation at the Shadow Robot Company.

5. SOUNDBITE (English) Armando De La Rosa, head of dexterous manipulation at the Shadow Robot Company:

"Especially for dangerous environments where often you need - if you think of in bomb disposal and nuclear commissioning, this is often where you need human dexterity but you don't want a human nearby. This can be attached to a robot arm, to a little rover, and send it on its way and you have the operator somewhere else, at a safe distance, being able to remotely operate the hand to do whatever needs doing and if something goes wrong the operator is at no risk."

6. Various of Shadow Dextrous Hand being operated by Armando De La Rosa, head of dexterous manipulation at the Shadow Robot Company.

7. SOUNDBITE (English) Armando De La Rosa, head of dexterous manipulation at the Shadow Robot Company:

"Robots are just going everywhere, in our homes, into space, into industry so the dream is not just in space but just robots everywhere making everybody's life better."

8. Various of visitors looking at exhibits at the UK Robotics Week event

9. Various of Dr Saeed Zahedi, technical director at Blatchford, with the Linx Limb.

10. SOUNDBITE (English): Dr Saeed Zahedi, technical director at Blatchford.

"This is the first integrated limb where the ankle and knee, they talk to each other, and behave in a coordinated manner. So for example if the amputee is going down the slope it would provide a break at the ankle as well as a break at the knee. An array of sensors at the knee and the ankle, they provide the information to each other so it can coordinate and synchronise and predict what the person is going to do in the same manner as you and I will go down the slope or go up the slope or go down the stairs or stand. Therefore the effort an amputee has to put into walking a leg will reduce."

11. Various of robotics on display at the UK Robotics Week event.

WORLD 2017 PREDICTIONS

SOURCE: AP HORIZONS, LIFESTYLE, HEALTH AND TECHNOLOGY/POOL

RESTRICTIONS: HORIZONS CLIENTS AND AP LIFESTYLE, HEALTH AND TECHNOLOGY CLIENTS ONLY

LENGTH: 7:28

SHOTLIST:

AP Television

New York - 9 November 2016

1. Various of Trump fans celebrating

2. Wide of Trump and his family

3. Woman celebrating Trump's win

4. Trump and family walking on stage

5. People cheering Trump

6. Trump shaking hands with Mike Pence

Miami - 11 November 2016

7. Various of anti-Trump protests

New York - 1 December 2016

8. SOUNDBITE (English) Beth Ann Bovino, Chief U.S. Economist, S&P Global Ratings:

"In terms of the impact of the Trump presidency on growth, you have to keep in mind that right now campaign promises are just what they are, promises, they are not policies. So let's see what happens in terms of how they get through Congress and whether.. and basically what comes out at the end."

Washington - recent

9. Exterior of US Capitol

New York, US - 13 June 2014

10. New York Mercantile Exchange (NYMEX) floor

US - Exact date and location unknown

11. Man filling up car at petrol station

New York - 1 December 2016

12. SOUNDBITE (English) Beth Ann Bovino, Chief U.S. Economist, S&P Global Ratings:

"If you look at the job gains now averaging around 180,000 per month for the year to date and the unemployment rate under 5 percent we have a rather strong jobs market, so in terms of actually pushing the unemployment rate down even further and strengthening the jobs market that might actually result in stronger inflation as well, making the fed likely having to move further."

Moscow, Russia — December 15, 2016

13. Various of Kremlin

14. Various of political analyst Masha Lipman looking at computer

15. SOUNDBITE (English) Masha Lipman, political analyst:

"We used to say that Putin is unpredictable and keeps his intentions and his plans as secret. Now we have at least one more person, who is unpredictable and this is the President of the United States - President-elect at this point, but of course in 2017, he will become the President of the United States. We still know very little about his policies. His appointments leave many shocked and speechless even, shaking heads in this belief. But what his policies are going to be is an open question. "

Aleppo, Syria - 15 December 2016

16. Wide of Aleppo outskirts

17. Wide of buses parked near evacuation area

18. Various of United Nations vehicles parked near evacuation centre

Bartella, Iraq - 21 October 2016

19. Various of Bartella, east of Mosul during fight against IS group

20. Various of Iraqi Special Forces

Cairo, Egypt - 13 December 2016

21. Set up of Dr. Saeed Sadek Political Sociology Professor at Future university in Cairo at office

22. SOUNDBITE (English) Saeed Sadek, Political Sociology Professor at Future university in Cairo:

"The only problem for the Iraqi people is of course they have this ethnic and religion sectarian conflict may continue and erupt here and there from fanatics on both sides, corruption and oil prices will also affect the Iraqi economy for 2017."

London, UK - 13 July 2016

23. Various of British flag on parliament

UK Pool

London - 27 June 2016

24. British PM Teresa May ( formerly Home Secretary) arriving at 10 Downing Street

AP Television

Berlin, Germany - 12 July 2016

25. Various of German newspaper headlines about Teresa May

26. Various of German Chancellor Angela Merkel

Berlin - 1 December 2016

27. Various of the German Parliament building (Bundestag)

28. Thorsten Benner, director of the Global Public Policy Institute (GPPi) in Berlin, in his office

29. SOUNDBITE: (English), Thorsten Benner, director of the Global Public Policy Institute (GPPi) in Berlin:

"The AFD (Alternative Fuer Deutschland) is actually taking away quite a few voters from the Christian Democrats. And it is a very unfortunate thing for Merkel to have a party formed to her right. That indeed is a vital threat to her political ambitions."

Surat, India - 5 December 2016

30. Various of men working in Indian diamond factory

New Delhi, India – 3 December 2016

31. Various of economist Veena Jha in her office

32. SOUNDBITE (English) Veena Jha, Economist:

"India has to consolidate its trade relationships within Asia. It has to look to Europe, without Britain, for a strong trade relationship. It has to solidify its relationships, particularly, with Germany, Netherlands, and France, which are the largest markets. It has to look to the US for an Indo-US free trade agreement and kind of a strategic partnership which has been talked about but has not been inked."

New Delhi, India – 7 November 2016

33. British Prime Minister Theresa May shakes hands with her Indian counterpart Narendra Modi during her official visit to India

Surat, India - 5 December 2016

34. Various street scenes in Surat

Rojama Mayong Village, Assam, India – 18 November 2016

35. A woman waiting to exchange defunct currency bills at a bank

Beijing, China - 30 November 2016

36. Various of Chinese Feng Shui master and astrologist Dong Yilin

37. SOUNDBITE (Mandarin) Dong Yilin, Chinese Feng Shui Master and Astrologist:

"In the year of the rooster, the Heavenly Stem (in Yi Qing) is fire and the Earthly Branch is gold and they are struggling with each other. It's like a process of burning gold and beating it into a craftwork. The craftwork is beautiful but it has to go through enormous hardships. Therefore, in the year of 2017, we will see many "turmoils" not only in China but also many other parts of the world like Europe and the US."

38. Close of compass

LEADIN

2016 has been a year of upheavals and upsets that some would prefer to forget.

So what can we expect in 2017? Will the year of the rooster change the world pecking order or will it be business as usual?

While analysts are mixed on what lies ahead, one Chinese fortune teller says the world can expect "turmoil".

STORYLINE

It was a result few people predicted, but one which will play a major role in shaping the year ahead.

Donald Trump's inauguration as the 45th US President will be held on January 20th and it's expected to draw people of all persuasions to Washington whether it's to celebrate or commiserate.

His stunning election win sparked numerous protests, and it's provoked widespread speculation about the impact that some of his controversial campaign promises might have when he takes office in 2017.

Chief U.S. Economist with S&P Global Ratings, Beth Ann Bovino says there's still some uncertainty over what path he will take.

"In terms of the impact of the Trump presidency on growth, you have to keep in mind that right now campaign promises are just what they are, promises, they are not policies. So let's see what happens in terms of how they get through Congress and whether.. and basically what comes out at the end."

If there are no major shocks to the economy, growth is expected to be around 2.5 percent and more interest rate rises are likely, according to Bovino.

"If you look at the job gains now averaging around 180,000 per month for the year to date and the unemployment rate under 5 percent we have a rather strong jobs market, so in terms of pushing the unemployment rate down even further and strengthening the jobs market that might actually result in stronger inflation as well, making the fed likely having to move further," she says.

In light of CIA accusations of Russian hacking, Trump's relations with the Kremlin will come into focus in January.

The Senate Foreign Relations Committee plans to hold an open hearing that will examine possible Russian meddling in November's presidential election.

Political analyst Masha Lipman says there are signs Moscow's relationship with Washington will thaw, but adds that both leaders are not giving much away just yet.

"We used to say that Putin is unpredictable and keeps his intentions and his plans as secret. Now we have at least one more person, who is unpredictable and this is the president of the United States — President-elect at this point, but of course in 2017, he will become the president of the United States. We still know very little about his policies. His appointments leave many shocked and speechless even, shaking heads in disbelief. But what his policies are going to be is an open question."

Lipman says the ongoing civil war in Syria means Trump and President Putin will need to make some tough choices.

Syria has been torn apart by more than five years of war - at the moment both countries support different sides.

Over the border, the Iraqi special forces are still battling the Islamic State group, also known as Daesh.

UK Defence Secretary Michael Fallon says that "Daesh is now failing and controls less than 10 percent of Iraqi territory."

Political Sociology Professor at Future university in Cairo, Saeed Sadek says even if Daesh is eventually defeated, Iraq could still face many challenges.

"The only problem for the Iraqi people is off course they have this ethnic and religion sectarian conflict may continue and erupt here and there from fanatics on both sides corruption and oil prices will also affect the Iraqi economy for 2017," he says.

2017 will also see Britain set the wheels in motion for its exit from the European Union.

Prime Minister Teresa May has set a March deadline to start Brexit and will face 2 years of tense debate as she tries to get the UK the best deals on trade.

German Chancellor Angela Merkel says Britain faces "rough" and "hard" negotiation. But Merkel also faces a fight for her own survival with elections later in the year.

Germany will elect the members of the Bundestag, as the German parliament is called, after the summer in 2017.

Merkel's Christian Democrats are currently in a coalition government with the Social Democrats (SPD).

However, the Global Public Policy Institute (GPPI) in Berlin says there has been a right wing backlash because of her policy welcoming Syrian refugees.

"The AFD (Alternative Fuer Deutschland) party is actually taking away quite a few voters from the Christian Democrats. And it is a very unfortunate thing for Merkel to have a party formed to her right. That indeed is a vital threat to her political ambitions," says GPPI director Thorsten Benner.

While the West slows, the one jewel in the world economic crown is likely to be India as its growth outperforms the rest of the world.

Veena Jha, an economist and policy analyst, says India's economy is now growing faster than China and the country must seek new markets.

She says Britain could be the biggest loser because Brexit will slow Indian investment in the UK as it looks elsewhere.

"India has to consolidate its trade relationships within Asia. It has to look to Europe, without Britain, for a strong trade relationship. It has to solidify its relationships, particularly, with Germany, Netherlands, and France, which are the largest markets. It has to look to the US for an Indo-US free trade agreement and kind of a strategic partnership which has been talked about but has not been inked."

However there could be hiccups as Indian Prime Minister Narendra Modi moves towards a cashless society, promoting digital transactions instead to curb the black market.

However the coins fall, 2017 is the Chinese Year of the Rooster which begins on January 28th. The Rooster is the sign of dawn and awakening, but it also means that triumph can only be achieved at the price of hard work.

Chinese Feng Shui Master and Astrologist Dong Yilin says many countries will face huge challenges with their economies.

"In the year of rooster, the Heavenly Stem (in Yi Qing) is fire and the Earthly Branch is gold and they are struggling with each other. It's like a process of burning gold and beating it into a craftwork. The craftwork is beautiful but it has to go through enormous hardships. Therefore, in the year of 2017, we will see many "turmoils" not only in China but also many other parts of the world like the Europe and the US."

One thing's for certain, a busy 2017 awaits whatever way the compass points.

====

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As Britain prepares for a sharp economic break with the EU, an uncertain future awaits one bike manufacturer, which fears not having enough reserve supplies following turbulence caused by the coronavirus pandemic.

The team at Brompton Bicycle Ltd., which exports its hand-made folding bikes to 47 countries, thought they were prepared for Brexit, having stockpiled parts.

But then, the coronavirus pandemic struck.

Orders dried up as stores were closed during lockdown in the spring, only to surge once it was lifted.

"We struggled to get the parts back in again," said Brompton chief executive Will Butler-Adams.

"So we've had to eat into our Brexit stock, which has saved us in many respects. But ... we're now sitting here with a month to go and we've got no Brexit stock and we're facing Brexit."

Another worry for Butler-Adams is the government's decision to abolish an anti-dumping tariff imposed by the EU on Chinese bicycles after Brexit.

Brompton and other British manufacturers say removing the 48.5% tax will flood the market with cheap bikes subsidized by the Chinese state.

The U.K. split from the EU politically early this year, but remained part of the bloc's economic embrace during an 11-month transition as the two sides tried to negotiate a new free-trade deal to take effect Jan. 1.

But months of tense and often testy negotiations have not resolved differences on fishing rights, fair-competition rules and how to resolve future disputes.

Intense talks must produce either a breakthrough or a final breakdown in the coming days.

If there is no deal, New Year's Day will bring tariffs and other barriers to U.K.-EU trade, hurting economies on both sides of the English Channel.

The burden will fall most heavily in Britain, which does almost half its trade with the EU.

Things will be smoother with a deal, which would remove quotas and tariffs on goods, though business still face new obstacles and red tape.

Trade expert David Henig of the European Centre for International Political Economy said Jan. 1 marks "the biggest one-day change in trading relations that any country since 1945 will have experienced."  

"This is going from a permissive regime, where more or less we can trade anything with the EU that we like, to a permission-based one where we have to check for everything that we want to trade — whether that's goods or services — whether we're allowed to do it," he said.

London - 24 November 2020

1. Worker in Brompton Bicycle factory turning pedal bar on upturned bike

2. Worker tightening bike part

3. Worker twisting handle bars

4. Brompton Bicycle chief executive Will Butler-Adams walking along production line

5. Worker screwing part into wheel

6. SOUNDBITE (English) Will Butler-Adams, Brompton Bicycle chief executive:

"We put in place plans for the worst case scenario, and then we forgot about it, really, and got back to running our business and didn't spend three years getting distracted worrying about what might happen with Brexit. And that was all great. But of course, then COVID came along, and we'd built up this fantastic stock, for the worst case Brexit scenario, but then, when we went into the corona crisis, we stopped ordering because it was terrifying, and orders fell off a cliff and all our shops closed."

7. Pan across factory floor

8. SOUNDBITE (English) Will Butler-Adams, Brompton Bicycle chief executive:

"When we came out of COVID, suddenly demand, which we hadn't anticipated - maybe we should have done - went totally bananas, so then we were like "turn it on again, turn it on again," so did the whole rest of the industry, so then we struggled to get the parts back in again, so we've had to eat in to our Brexit stock, which saved us in many respects, but it now means, having been prudent and got it all organized like three years ago, we're now sitting here with a month to go, and, we've got no Brexit stock and we're facing Brexit."

9. Pan down boxes of parts

10. Various of workers welding parts

11. SOUNDBITE (English) Will Butler-Adams, Brompton Bicycle chief executive:

"Anti-dumping actually means that the country where the product is coming from is subsidizing that industry, i.e. you don't have to pay for your rent, your materials, your electricity is costing you a lot less than the actual going rate. What that does is, it means that it's not fair. The state is subsidizing that industry to make it so competitive that it's uncompetitive, we can't compete."

12. Worker putting wheel together

13. Worker placing part on mud guard

14. Bike pushed across production floor, pan to wheel being folded away

15. Bikes on production line

16. Sign reading (English) "Assembly Line 1," listing number of bikes built and packed, sign changing to "100%"

17. European Centre for International Political Economy trade expert David Henig walking towards road

18. Cyclists on road

19. SOUNDBITE (English) David Henig, trade expert at the European Centre for International Political Economy:

"It's probably the biggest change, one day change, in trading relations that any country since 1945 will have experienced. This is a huge change. This is going from a permissive regime where more or less we can trade anything with the EU that we like, to a permission based one where we have to check that everything that we want to trade, whether that's goods or services, whether we're allowed to do it."

20. Wide of London street with cyclists and traffics