As British business owners try to come to terms with the vote to leave the European Union, there are fears of the implications a "Brexit" will have.

London perfume maker, Sarah McCartney, said her businesses future "is not smelling so sweet at the moment".

She said she relies on trade with Europe and not only has the cost of raw materials increased, so too will the amount of paper work.

International trade lawyer, Miriam Gonzalez, said trying to minimise businesses uncertainty should be the governments top priority.

She said businesses need to know what the framework for Britain's negotiations with the EU will be, so they can try and minimise uncertainty.

City of London Corporation Policy Chairman, Mark Boleat, said that those uncertainties mean that "some investment is certainly going to be deterred."

While Edwin Morgan from Institute of Directors said the unknowns mean two thirds of its members think a "Brexit" will be negative for their business and cutting investment, redundancies and relocating are all on the table.

London - 27 June 2016

1. Perfume maker Sarah McCartney working in her factory in west London

2. Close of essence being poured

3. Close of perfume essence being bottled

4. Cap being placed on vial

5. Perfume label reading (English) "Inevitable Crimes of Passion"

6. Label being stuck on vial

7. Finished vials

8. SOUNDBITE (English) Sarah McCartney, 4160 Tuesdays perfume maker:

"I make perfume and the future is not smelling so sweet at the moment. I deal with France and Germany, I buy raw materials from Europe, I sell to Europe. I just think it's going to get a heck of a lot more complicated, and it's already got more expensive."

9. Various of McCartney during interview

10. SOUNDBITE (English) Sarah McCartney, 4160 Tuesdays perfume maker:

"Our market is worldwide and I really, really need to trade with Europe. I buy raw materials from Europe and suddenly they're going to be, well at least, eight per cent more expensive and probably there's going to be ten times as much paperwork."

11. McCartney making perfume

12. Perfume bottles made by 4160 Tuesdays

13. Various of commuters in the City of London

14. Various of financial institutions

15. SOUNDBITE (English) Miriam Gonzalez, International Trade Lawyer:

"There are only a few companies that have really done the nitty-gritty homework to be ready for Brexit. Many of them, they were kind of hoping that it would not happen, so now is the time that they really need to start doing that work."

16. Cutaway of Gonzelez's hands

17. SOUNDBITE (English) Miriam Gonzalez, International Trade Lawyer:

"This country, the businesses in this country need to know what is the framework that the government is aspiring to negotiate, and therefore, whether that is the single market, remaining in the single market or not makes a crucial difference. Trying to minimise the legal uncertainty, I would have thought that is the top priority."

18. Various of painting by John Single Copley called "The Defeat of the Floating Batteries at Gibraltar"

19. SOUNDBITE (English) Mark Boleat, City of London Corporation Policy Chairman:

"I think the authorities have handled the market turmoil as well as they could have done. That was done carefully on Friday and no doubt is continuing today but that's a short term issue. It's some of these longer issues that need resolving. It remains to be seen what impact this will have on the growth of the British economy over the next few months, what impact on tax revenue, what impact on foreign direct investment."

20. Cutaway of painting

21. SOUNDBITE (English) Mark Boleat, City of London Corporation Policy Chairman:

"The fundamentals remain unchanged, Britain is still a very attractive place for business and for investment, but given those sort of uncertainties some investment certainly going to be deterred. Very much depends what the sector is, how important membership of the single market is. But we are going to see some uncertainty and that's going to have an affect on investment."

22. Boleat walking

23. Various aerials of London's business district, Canary Wharf

24. Various exteriors of Parliament

25. Edwin Morgan, Head of Media Relations, Institute of Directors

26. Cutaway of report

27. SOUNDBITE (English) Edwin Morgan, Head of Media Relations, Institute of Directors:

"We asked our members immediately after the referendum result came in, what they thought, how they thought it would affect their businesses. Two thirds said that it was negative for them against only about a quarter who thought it was positive. On the specific questions we asked, we asked about investment and hiring decisions and there was also some quite worrying figures. About 36 percent of our members think that they will have to cut investment as a result and about 5 percent of our members say they might have to make redundancies which is obviously quite worrying. There are also some other figures in there on whether or not they'll keep all their operations in the UK or whether they may be forced to move overseas. About 1 in 5 are considering, as we speak, moving some of their operations out of the UK, whether that's to the EU or to somewhere outside it. I mean ultimately we think that our members are very resilient, we think British business is tough and will get through it and will adapt, but certainly at the moment there is a lot of nervousness out there in the business community."

28. Cutaway of report

CHRISTOPHER KANE UNVEILS NEW COLLECTION; CAROLINE RUSH TALKS BREXIT

British designer Christopher Kane unveiled his new spring/summer 2017 at London Fashion Week, Monday (19 SEPT. 2016).

The show was attended by U.S. Vogue editor-in-chief Anna Wintour, model Poppy Delevingne and Caroline Rush, Chief Executive of the British Fashion Council.

Rush described the collection - which featured bold prints and metallic shades - as a highlight of London Fashion Week so far.

"It's hard not to reference him as a true innovator. There was a real play on fabrication... there was a reference to his graduate collection - but beautifully made and pulled together. I think everyone has walked out saying that has set the bar," she said.

With fashionistas from all over the world flocking to London for the five day event, Rush also discussed whether the U.K.'s recent vote to leave the European Union has been bad for business.

"There's been a lot of talk about Brexit over the last few days - of course, it's the first fashion week post the vote. But, over the summer months we've seen a bounce in luxury and retail sales and I think there's a slow element of confidence," she said

"It's definitely not something that the industry wanted, but like any business decision or challenge, you look for the opportunities in it and you overcome the challenges when they come."

London Fashion Week draws to a close on Tuesday, 20 September.

AP Entertainment - Music on catwalks not cleared for use. Please replace with your own Clearable Music

London, 19 September 2016

1. Wide shot interior of venue

2. Medium shot model Poppy Delevingne

3. Various shots Christopher Kane spring/summer 2017 collection

4. Various shots final pass

5. Wide of designer Christopher Kane receiving applause (Anna Wintour in shot at end of show)

6. SOUNDBITE (English) Caroline Rush, Chief Executive of the British Fashion Council - on Christopher Kane's show:

"Well we've had an incredible four days so far. We've got one day to go. I've just come out of the Christopher Kane show and it's hard not to reference him as a true innovator. There was a real play on fabrication, on different takes and references to previous - there was a reference to his graduate collection - but beautifully made and pulled together and I think everyone has walked out saying that has set the bar and let's see what's to follow."

7. Medium shot Caroline Rush walking

8. SOUNDBITE (English) Caroline Rush, Chief Executive of the British Fashion Council - on whether Britain's vote to leave the European Union is impacting the fashion industry:

"Well, there's been a lot of talk about Brexit over the last few days - of course, it's the first fashion week post the vote. But over the summer months we've seen a bounce in luxury and retail sales and I think there's a sort of slow element of confidence. It's definitely not something that the industry wanted, but like any business decision or challenge, you look for the opportunities in it and you overcome the challenges when they come."

9. Wide shot Caroline Rush walking

US Secretary of State John Kerry addressed the Oxford Union on Wednesday, speaking on a diverse range of issues, including corruption, Brexit and the problems that face Syria.

Kerry, who planned to attend UK Prime Minister David Cameron's anti-corruption conference on Thursday, appeared to give the prime minister some political cover by describing Nigeria's corruption as a problem its current leaders were working faithfully to address.

Fielding a question on Brexit, he reiterated US President Obama's stance that the US would be looking to make a trade agreement with 27 countries, not one.

Kerry also said that if Russia and Iran don't push Syrian President Bashar Assad to embrace their vision for Syria's future, the there ceasefire would completely fall apart.

US Secretary of State John Kerry addressed the Oxford Union on Wednesday, speaking on a diverse range of issues, including corruption, Brexit and the problems that face Syria.

Kerry, who planned to attend UK Prime Minister David Cameron's anti-corruption conference on Thursday, appeared to give the prime minister some political cover by describing Nigeria's corruption as a problem its current leaders were working faithfully to address.

Fielding a question on Brexit, he reiterated US President Obama's stance that the US would be looking to make a trade agreement with 27 countries, not one.

Kerry also said that if Russia and Iran don't push Syrian President Bashar Assad to embrace their vision for Syria's future, the there ceasefire would completely fall apart.

Oxford - 11 May 2016

1. US Secretary of State John Kerry enters Oxford Union

2. Various of audience

3. SOUNDBITE (English) John Kerry, US Secretary of State:

"We have to stop and ask on an international basis how it is that a bunch of generals in a country like Nigeria, which had happened previously, and the new president (Buhari) has run against all this, and we are working with him now to change it, but Nigeria saw tens of billions of dollars taken out of the country. Those were schools, those were health care, those were infrastructure, new jobs, hidden in bank accounts around the world."

4. Cutaway

5. SOUNDBITE (English) John Kerry, US Secretary of State:

"We believe the presence of Britain in EU magnifies its voice, strengthens its ability to be able to impact on global effects, and if indeed the decision were made and your voters make that decision, of course we respect it. But the reality is that in a trade agreement, we're going to be looking to 27 countries, not one. We're going to try and maximize the market place and get the rules in as many countries as we can, because that's the way it's effective, so certainly it will have impacts like that."

6. Cutaway

7. SOUNDBITE (English) John Kerry, US Secretary of State:

"A political negotiation, a transitional governance body that would run Syria while the constitution is being written and implemented, and then a cease-fire, nation-wide and then and election in a year and a half. Now we are now already five months in so it would be a year and whatever. But that's the envisioned outcome of Iran and Russia. It's pretty similar to ours. The issue is are they going to really push (Syrian President) Assad to embrace it. If he doesn't, the ceasefire will completely fall apart, they will go back to war baring some other kind of intervention that I don't necessarily see on the horizon right now."

8. Kerry finishes Oxford address to applause